L'Occitane Immortelle Precious Eye Balm for mature skin

Questions and answers

What the research says

• Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.

  International Journal of Cosmetic Science, 2018

• Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events.

  Journal of Cosmetic Dermatology, 2019

• Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

  International Journal of Molecular Sciences, 2026

• Polypropylene non-woven fabric impregnated with H. italicum extract using ethanol as a cosolvent demonstrated significantly greater potential for skin protection compared to other investigated samples on artificially irritated human skin without causing irritation or redness.

  Journal of Ethnopharmacology, 2023

• Application of creams and emulgels containing immortelle extract and hemp oil increased skin hydration and reduced TEWL in 25 healthy volunteers compared to placebo samples and a non-treated control, with emulgels demonstrating enhanced herbal active delivery and better sensory properties than creams.

  Pharmaceutics, 2021

• A night cream containing melatonin, carnosine, and Helichrysum italicum extract reduced oxidative stress ex vivo and improved hydration, reduced transepidermal water loss, decreased wrinkles and spots, and lowered skin reactivity in 117 individuals over up to 12 weeks of nightly use.

  Dermatology and Therapy, 2020

• Neryl acetate mediates a large part of Corsican Helichrysum italicum essential oil activity by upregulating genes involved in epidermal differentiation, skin barrier formation, and ceramide synthesis, leading to increased involucrin, total lipids, and ceramides in human skin explant models compared to the essential oil.

  PloS One, 2023

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks.

  International Journal of Cosmetic Science, 2011

• Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects.

  Frontiers in Physiology, 2019

• Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid.

  AAPS PharmSciTech, 2021

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Topical escin promotes angiogenic behavior and enhances adenosine-induced perfusion in humans by activating Wnt signaling via Gsk3beta down-regulation.

  Current Issues in Molecular Biology, 2025

• External use of escin reduced acute and chronic cutaneous inflammation and edema in rat and mouse models by down-regulating PGE2, TNF-α, and IL-1β, promoting glucocorticoid receptor expression, and inhibiting NF-κB and AP-1 expressions.

  Chinese Journal of Natural Medicines, 2018

Ingredients

Water, Caprylic Capric Triglyceride, Glycerin, Silica, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Methylpropanediol, Helichrysum Italicum Oil Flower, Helichrysum Italicum Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Centaurea Cyanus Flower Water, Caffeine, Adenosine, Sodium Hyaluronate, Escin, Tapioca Starch, Caprylyl Glycol, Glyceryl Stearate Citrate, Tocopherol, Xanthan Gum, Sorbitan Isostearate, Polysorbate 60, Silanetriol, Citric Acid, Sodium Hydroxide, Chlorphenesin, Sodium Benzoate, Potassium Sorbate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.