🇫🇷France

HISTOLAB Soft Deep Cleansing Enzyme Powder Wash for mature skin

High

  • HighNormal Skin Fit
  • HighEffectiveness
  • ExcellentSafety

A great choice for mature skin; a few products fit it even better.

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate exfoliation for wrinkles and fine lines due to papain and bromelain, which provide enzymatic breakdown of dead skin cells, supporting desquamation regulation for your normal skin.
  • Cleanses pores effectively with Sodium Lauroyl Glutamate and Sodium Cocoyl Isethionate, while allantoin and tocopherol vitamin E offer soothing benefits.
  • The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of harsh ingredients and the presence of soothing components.

How to apply

  • Could be used as part of your PM routine once a week, increasing to 2-3 times if your skin tolerates it well.
  • Place this enzyme powder cleanser in your weekly routine after your regular cleanser and before your hydrating toner.
  • Mix a small amount of the enzyme powder cleanser with water in your hands to create a soft foam before applying.
  • Gently massage the foam onto your damp face using circular motions, then rinse thoroughly with warm water.
  • Avoid the sensitive eye area and always apply SPF the morning after using exfoliating products.

People Say

★4.0Overall rating based on 100+ reviews

Based on limited available data, users find this enzymatic cleanser to be gentle and effective, leaving skin soft and smooth without stripping natural oils. It is particularly beneficial for oily and acne-prone skin, helping to manage sebum and unclog pores. Some users note a learning curve for lathering the powder format.

Highlights

  • Gentle Exfoliation Often Mentioned
    • “leaves skin soft”
    • “non-stripping cleanse”
    • “gentle enzyme action”
  • Travel-Friendly Often Mentioned
    • “perfect for travel”
    • “compact size”
    • “easy to pack”
  • Good for Oily/Acne Skin Sometimes Noted
    • “reduces closed comedones”
    • “calms oily skin”
    • “good for breakouts”
  • Post-Wash Feel Sometimes Noted
    • “squeaky clean but soft”
    • “refreshed feeling”
    • “smooth complexion”
  • Lathering difficulty Sometimes Noted
    • “doesn't lather well”
    • “hard to foam”
    • “needs mixing effort”
  • Availability Rarely Noted
    • “inconvenient to buy”
    • “shipping takes long”
    • “niche product”
  • Price & Size Rarely Noted
    • “wish it was larger”
    • “expensive for size”
    • “hard to find”
  • Scent Rarely Noted
    • “acquired taste”
    • “scent is disappointing”
    • “odd smell at first”

Sources: lovi.care, histolab.ca, ubuy.com, hwahae.co.kr, ebay.com, gosupps.com, and more

Questions and answers

What makes HISTOLAB Enzyme Powder Wash a great fit for mature skin?

HISTOLAB Soft Deep Cleansing Enzyme Powder Wash is a great fit for mature skin because it offers gentle exfoliation with papaya and rice powder to help smooth wrinkles and fine lines. It cleanses pores effectively while soothing the skin with gentle ingredients, maintaining an excellent safety profile without harsh irritants.

Journal of Cosmetic Dermatology, 2020

Which ingredients make this cleanser a good fit for mature skin?

Papaya enzyme and bromelain gently smooth away dead skin cells to help soften wrinkles, while soothing ingredients like vitamin E keep mature skin calm. Ascorbic acid also helps brighten and improve skin texture.

Journal of Cosmetic Dermatology, 2020

What does Papaya Enzyme do for mature skin?

Papaya enzyme gently removes dead skin flakes to help keep your skin feeling soft and smooth. This process helps clear away old layers so your face looks fresh, though it is best used carefully since it may occasionally cause irritation on dry or sensitive areas.

International Journal of Cosmetic Science, 2024

What does Rice Powder do for mature skin?

Rice powder helps smooth out rough patches, softens fine lines, and improves overall skin elasticity for a more youthful look. It is also gentle enough to help calm dry or irritated areas while supporting the skin's natural barrier.

Molecules, 2022Journal of Cosmetic Dermatology, 2022

Where does this cleanser go in a skincare routine for mature skin?

This enzyme powder cleanser goes in your morning or evening routine, or once a week as an exfoliating step. It is very gentle and unlikely to cause irritation, helping smooth wrinkles and fine lines while leaving mature skin feeling soft and clean.

Can I use this cleanser with retinol, and in what order?

You can use this enzyme powder cleanser alongside retinol by adding it to your weekly routine rather than the same night you apply your retinol. Using them on separate days helps avoid over-exfoliating mature skin while still keeping pores clean and smooth.

How often should I use this cleanser?

Start using this enzyme powder cleanser once a week as part of your routine. If your skin tolerates it well and you see good results, you can carefully use it more often.

Can this cleanser clog pores, cause breakouts or purging for mature skin?

This cleanser is unlikely to clog pores, cause breakouts, or lead to purging on mature skin. It cleanses pores effectively while keeping irritation very low, thanks to gentle ingredients that help keep your skin calm and smooth.

Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Oral bromelain slightly reduced pain compared to controls (mean difference -0.27) and topical bromelain reduced time to complete debridement by 6.89 days, with no major health risks reported.

    Nutrition and Health, 2023
  • A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

    Journal of Cosmetic Dermatology, 2020
  • Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo.

    Wilderness & Environmental Medicine, 2016
  • A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face.

    Giornale Italiano Di Dermatologia E Venereologia, 2015
  • Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation.

    Molecules, 2020
  • Daily application of a cream containing niosomes loaded with purple glutinous rice extract in 20 human volunteers for 28 days resulted in a significant decrease in melanin index and skin roughness by -14.05% and -9.95%, and increases in skin hydration and elastic recovery by +48.73% and +35.98% compared to initial values.

    International Journal of Cosmetic Science, 2020
  • The iontophoretic delivery of hyaluronic acid nanogel-loaded Saccharomyces/Rice Ferment Filtrate significantly reduced advanced glycation end products and mitigated skin stiffening in an ex vivo skin tissue glycation model.

    International Journal of Nanomedicine, 2025
  • Red rice extract suppressed UVB-induced inflammation and skin aging in human skin fibroblasts by inhibiting the MAPK signaling pathway, leading to decreased NF-kappa B and AP-1 activation, reduced ECM degradation, and increased ECM synthesis compared to UVB-irradiated controls.

    Natural Product Communications, 2016
  • Oral sodium bicarbonate improved Yo-Yo IR2 distance by 21% and repeated sprint completion time by 1.9%, while topical sodium bicarbonate improved repeated sprint time by 2.0% without affecting Yo-Yo IR2 distance, in recreationally trained male athletes compared to placebo.

    Journal of the International Society of Sports Nutrition, 2023
  • Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.

    Journal of Clinical and Diagnostic Research, 2017
  • Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.

    Experimental Dermatology, 2009
  • An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.

    Clinical, Cosmetic and Investigational Dermatology, 2019
  • Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

    Experimental Dermatology, 2003
  • Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

    Journal of Periodontology, 2009
  • Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

    Journal of Cosmetic Dermatology, 2022

Ingredients

Sodium Lauroyl Glutamate, Sodium Cocoyl Isethionate, Papain, Bromelain, Sodium Bicarbonate, Silica, Allantoin, Tocopherol Vitamin E, Ascorbic Acid, Water

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.