Clé de Peau Beauté Hydro-Softening Lotion for dry skin

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Tremella fuciformis polysaccharides effectively alleviate UVA-induced photodamage in human dermal fibroblasts by reducing ROS and MDA, increasing antioxidant enzyme activities, up-regulating Nrf2 while down-regulating Keap1 expression, and increasing collagen I, elastin, and hyaluronic acid content.

  Journal of Cosmetic Dermatology, 2021

• A topical formulation containing panthenol, niacinamide, and dipotassium glycyrrhizate increased skin hydration by 74.1% and reduced transepidermal water loss by 13.5% at 28 days compared to baseline and untreated control in 35 individuals with xerosis.

  Journal of Cosmetic Dermatology, 2026

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Bacterial cellulose wound dressing containing silk sericin and PHMB improved wound quality and reduced pain compared to Bactigras in patients with split-thickness skin graft donor-site wounds.

  Archives of Dermatological Research, 2018

• A bacterial nanocellulose wound dressing incorporating polyhexamethylene biguanide and sericin showed no skin irritation in healthy volunteers and significantly promoted wound healing with lower wound size and higher collagen formation in full-thickness rat wounds compared to controls.

  Archives of Dermatological Research, 2016

• Topical application of sericin gels increased skin intrinsic moisturization, hydroxyproline content, and epidermal hydration while decreasing transepidermal water loss and skin impedance in healthy human volunteers.

  Journal of Cosmetic Dermatology, 2005

• Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers.

  Journal of Cosmetic Dermatology, 2021

• Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models.

  Archives of Dermatological Research, 2023

• Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts.

  In Vivo, 2022

• Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.

  Evidence-based Complementary and Alternative Medicine, 2015

• Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.

  Experimental Dermatology, 2015

• Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.

  Advanced Science, 2025

Ingredients

Water, Butylene Glycol, Dipropylene Glycol, Glycerin, Peg Ppg-14 7 Dimethyl Ether, Peg-8, Trehalose, Phenoxyethanol, Methyl Gluceth-10, Ppg-13-Decyltetradeceth-24, Theanine, Methylparaben, Disodium Edta, Erythritol, Sodium Citrate, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Polyquaternium-51, Tremella Fuciformis Polysaccharide, Citric Acid, Xylitol, Sodium Acetylated Hyaluronate, Parfum, Angelica Acutiloba Root Extract, Paeonia Albiflora Root Extract, Serine, Glycine, Scutellaria Baicalensis Root Extract, Rosmarinus Officinalis Leaf Water Rosemary Leaf Water, Hydrolyzed Silk, Ci 15985, Tocopherol, Perilla Ocymoides Leaf Extract, Yellow 5 Ci 19140, Benzoic Acid, Prunus Speciosa Leaf Extract, Fructose, Isodonis Japonicus Stalk Extract Leaf, Hydrolyzed Conchiolin Protein, Peg-30 Phytosterol, Hydrogenated Lecithin, Trisodium Edta

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.