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Biossance 100% Squalane Oil for dry skin

Biossance 100% Squalane Oil
  • Squalane
  • Squalane Oil

High

  • HighDry Skin Fit
  • HighEffectiveness
  • ExcellentSafety

A great choice for dry skin; a few products fit it even better.

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Highly suitable for your dry skin as squalane provides excellent emollient action to smooth intercellular lipids and reduce water loss, offering significant hydration for dry or flaky skin.
  • The high concentration of squalane enhances barrier resilience and offers excellent moisturizing benefits.
  • The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients and the presence of soothing ingredients.

People Say

★4.7Overall rating based on 2.5k+ reviews

This sugarcane-derived oil is widely praised as a "holy grail" for its lightweight, non-greasy texture that mimics the skin's natural moisture. Users with sensitive and acne-prone skin frequently report that it hydrates without clogging pores, while many appreciate its versatility as a multi-purpose treatment for face, body, and hair. This summary is based on a very large amount of data and should definitely be taken into account.

Highlights

  • Lightweight non-greasy Mostly Mentioned
    • “soaks in right away”
    • “doesn't feel heavy”
    • “leaves a nice glow not grease”
    • “feels like nothing on skin”
  • Multi-purpose versatility Often Mentioned
    • “tames frizzy hair”
    • “great on dry cuticles”
    • “mixes well with foundation”
    • “healed cracked elbows”
  • Softens skin texture Often Mentioned
    • “skin feels like velvet”
    • “plumps fine lines”
    • “makes face super soft”
    • “got rid of dry patches”
  • Soothing gentle Sometimes Noted
    • “stopped the flaking”
    • “no stinging on sensitive skin”
    • “safe for fungal acne”
  • Packaging pump issues Sometimes Noted
    • “pump leaks everywhere”
    • “dispenses too much product”
    • “messy cap”
    • “bottle gets oily”
  • Caused breakouts Rarely Noted
    • “gave me cystic acne”
    • “caused tiny whiteheads”
    • “clogged my pores”
    • “rash appeared after use”
  • Insufficient hydration Rarely Noted
    • “sat on top of skin”
    • “still felt dry later”
    • “needed a cream over it”
    • “too thin for winter”
  • Price point Rarely Noted
    • “pricy for just squalane”
    • “The Ordinary is cheaper”
    • “not worth the splurge”
    • “paying for the brand”

Sources: lovi.care, biossance.com, sephora.ph, kohls.com, influenster.com, sephora.com, and more

Questions and answers

What makes Biossance Squalane Oil a great fit for dry skin?

Biossance 100% Squalane Oil is a great fit for dry skin because it smooths skin and prevents water loss, keeping your face soft and deeply moisturized. Squalane strengthens your skin barrier and has a very safe, soothing profile that is unlikely to cause irritation.

Journal of Nanobiotechnology, 2025Molecules, 2025

Which ingredients make this oil a good fit for dry skin?

Squalane and Squalane Oil make this a great fit because they lock in moisture and help soothe flaky skin. This helps keep your dry skin feeling soft and smooth without any irritation.

Journal of Nanobiotechnology, 2025Molecules, 2025

What does Squalane do for dry skin?

Squalane helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture and prevents water loss. It is unlikely to cause irritation and may protect the skin from damage while improving overall hydration.

Advances in Food and Nutrition Research, 2012Molecules, 2009

What does Squalane Oil do for dry skin?

Squalane oil helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture. It is unlikely to irritate and may help repair the skin barrier through antioxidant activity.

Molecules, 2009Advances in Food and Nutrition Research, 2012

Where does this oil go in a skincare routine for dry skin?

Biossance 100% Squalane Oil goes in your moisturizer step to help lock in hydration and smooth dry or flaky skin. It is a great fit for your dry skin because it provides deep moisture and helps strengthen your skin barrier without causing irritation.

The Journal of Dermatological Treatment, 2022Journal of Nanobiotechnology, 2025

Can I use it with retinol, and in what order?

You can use this product alongside retinol, applying it after your retinol treatment to help lock in moisture and calm any potential dryness. Using a barrier-enhancing moisturizer alongside retinoids is unlikely to cause irritation and may help support your skin during treatment.

Cutis, 2006

How often should I use this oil?

You can use this oil daily as part of your morning and evening routine to help keep your dry skin soft and hydrated. It is very gentle and unlikely to cause irritation.

The Journal of Dermatological Treatment, 2022Journal of Nanobiotechnology, 2025

Can it clog pores, cause breakouts or purging for dry skin?

Biossance 100% Squalane Oil is unlikely to cause breakouts for dry skin since it has a great safety profile and a low complaint rate, though individual reactions can always vary. Squalane works gently to lock in moisture without clogging pores.

What the research says

  • Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

    Molecules, 2025
  • Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

    Antioxidants, 2025

Ingredients

Squalane, Squalane Oil

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.