Biologique Recherche Crème Dermopurifiante for acne-prone skin
Niacinamide
Mimosa Tenuiflora Extract
Centella Asiatica Extract
Arnica Montana Extract
Salicylic Acid
Average
- AverageCombination Skin Fit
- HighEffectiveness
- HighSafety
Works for acne-prone skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- This formulation offers moderate suitability for your combination skin, as niacinamide and Enantia Chlorantha Bark Extract provide seboregulating action to help mattify and reduce blemishes. Arctium Lappa Root Extract also contributes to managing acne and breakouts, though stronger ingredients might be needed for optimal results in all areas.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
- Functionally, it provides excellent treatment for oily and acne-prone skin due to the presence of niacinamide and oleanolic acid in concentrations that help to mattify and reduce blemishes.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.7Overall rating based on 500+ reviewsUsers with oily, acne-prone, and congested skin frequently report that this cream effectively regulates sebum and clears breakouts without causing dryness. The distinct, often-mentioned yeasty scent is a common drawback, but the majority of users find the balancing, purifying, and redness-reducing benefits outweigh this sensory aspect.
Highlights
Clears acne Mostly Mentioned
- “minimizes breakouts”
- “clears congestion”
- “eliminates blackheads”
- “prevents future acne”
Unpleasant scent Mostly Mentioned
- “smells like fish food”
- “yeasty/fermented smell”
- “funky fragrance”
- “earthy scent”
Balances oil production Often Mentioned
- “controls excess oil”
- “regulates sebum”
- “mattifies without drying”
- “skin feels balanced”
High price Often Mentioned
- “expensive”
- “pricey splurge”
- “investment product”
- “costly”
Hydrates without greasiness Sometimes Noted
- “lightweight hydration”
- “non-greasy finish”
- “absorbs well”
- “perfect makeup base”
Refines texture Sometimes Noted
- “shrinks enlarged pores”
- “refines skin texture”
- “smooths skin”
- “improves clarity”
Soothes redness Sometimes Noted
- “calms inflammation”
- “reduces redness”
- “soothes reactive skin”
- “even complexion”
Initial reaction Rarely Noted
- “skin turns red initially”
- “purging period”
- “tingling sensation”
Reformulation concerns Rarely Noted
- “less effective new formula”
- “not as hydrating”
- “preferred old version”
Texture issues Rarely Noted
- “brown/yellow color”
- “old fashioned texture”
- “feels heavy initially”
- “sticky finish”
Sources: lovi.care, shoprescuespa.com, paullabrecque.com, loshen.com, aidabicaj.com, reddit.com, and more
Questions and answers
How well does Crème Dermopurifiante work for acne-prone skin?
Biologique Recherche Crème Dermopurifiante works moderately well for acne-prone skin, helping to mattify and reduce blemishes with ingredients like niacinamide and salicylic acid. Because other products may fit this skin type better, acne-prone skin often needs stronger clarifying ingredients and soothing plant extracts like propolis or zinc PCA to clear breakouts and maintain balance.
Journal of Cosmetic Dermatology, 2024Chemical Biology & Drug Design, 2024
Which ingredients make this cream a good fit for acne-prone skin?
Niacinamide, salicylic acid, and oleanolic acid make this cream a good fit because they help control oil and reduce blemishes. To work even better for acne-prone skin, this type of product also needs strong targeted ingredients like propolis or zinc PCA to provide optimal care for breakouts while keeping the skin balanced.
Nanoscale Research Letters, 2020Journal of Cosmetic Dermatology, 2024
What does Niacinamide do for acne-prone skin?
Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
What does Mimosa Tenuiflora Extract do for acne-prone skin?
Mimosa Tenuiflora Extract helps support skin repair and encourages cell activity, which may benefit acne-prone skin dealing with lingering marks. Because this extract is typically found in wound-healing treatments, acne-prone skin using products of this type also needs ingredients that clear pores and calm active breakouts.
Journal of Ethnopharmacology, 2009Journal of Ethnopharmacology, 2007
Where does this cream go in a skincare routine for acne-prone skin?
This treatment goes in the evening routine after cleansing and toning, and can also be used weekly depending on your skin's tolerance. While it helps reduce blemishes and oiliness with ingredients like niacinamide, acne-prone skin often needs stronger targeted ingredients for optimal results.
Can I use this cream with retinol, and in what order?
You can use this cream alongside retinol by applying the retinol first at night, letting it dry, and then following with this treatment to help keep breakouts under control. This type of skin also needs stronger ingredients like retinoids or targeted acids for best results on stubborn breakouts.
How often should I use this cream?
Use this treatment in the evening as part of your nighttime routine. It is unlikely to irritate your skin, though an acne-prone skin type needs stronger ingredients like higher concentrations of salicylic acid or targeted retinoids for optimal results across all areas.
Can this cream clog pores, cause breakouts or purging for acne-prone skin?
This cream is unlikely to clog pores or cause purging for acne-prone skin, as it has a safe formula without harsh ingredients. It helps control oil and reduce blemishes with niacinamide and oleanolic acid, though acne-prone skin often needs even stronger clearing ingredients for the best results.
Nanoscale Research Letters, 2020Journal of Cosmetic Dermatology, 2024
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Arctigenin improved C. acnes-induced acne inflammation in mice by regulating E2 secretion and inhibiting the NLRP3 inflammasome signaling pathway through targeting CYP19A1.
Chemical Biology & Drug Design, 2024Polymeric micelles of oleanolic acid applied around the eyes of 23 female subjects for 8 weeks significantly improved all five optical profilometry skin parameters and visual evaluation scores without causing skin irritation.
Nanoscale Research Letters, 2020Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.
Journal of Cosmetic Dermatology, 2024Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Chitosan/Mimosa tenuiflora bio-composite films exhibited improved thermal stability, increased water-uptake ability, antibacterial properties against Escherichia Coli and Micrococcus, and were non-toxic in cytotoxicity assays.
International Journal of Biological Macromolecules, 2016Arabinogalactan-enriched fractions isolated from Mimosa tenuiflora bark significantly stimulated mitochondrial activity and proliferation in human primary dermal fibroblasts while having minor influence on HaCaT keratinocytes.
Journal of Ethnopharmacology, 2009Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans.
International Journal of Cosmetic Science, 2023Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin.
Cutaneous and Ocular Toxicology, 2020The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls.
International Journal of Experimental Pathology, 2023Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.
CMAJ, 2010A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.
BioMed Research International, 2020Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.
Journal of Cosmetic Dermatology, 2024
Why other serums fit acne-prone skin better
Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris.
The Journal of Clinical and Aesthetic Dermatology, 2020A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Water, Propylene Glycol, Glycerin, Dicaprylyl Carbonate, Butylene Glycol, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Polyamide-5, Arctium Lappa Root Extract, Betula Alba Bark Extract, Enantia Chlorantha Bark Extract Moambe Jaune Bark Extract, Equisetum Arvense Extract, Mimosa Tenuiflora Bark Extract Acacia Decurrens Bark Extract, Hedera Helix Stem Extract Leaf, Fucus Vesiculosus Extract, Centella Asiatica Extract, Spiraea Ulmaria Extract, Arnica Montana Flower Extract, Rosa Canina Fruit Extract, Achillea Millefolium Extract Common Yarrow Extract, Aesculus Hippocastanum Seed Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Thymus Vulgaris Extract, Myrtus Communis Extract, Onion Bulb Extract, Commiphora Myrrha Extract Resin, Oleanolic Acid, Glycine Soja Oil Soybean Oil, Yeast Extract, Citric Acid, Tocopherol, Sodium Stearoyl Glutamate, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, Caprylyl Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Sorbic Acid
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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