BIOEFFECT EGF Serum for dry sensitive skin
Rh-Oligopeptide-1
Glycerin
Sodium Hyaluronate
Hordeum Vulgare Seed Extract
Tromethamine
Superior
- SuperiorDry Skin Fit
- SuperiorEffectiveness
- ExcellentSafety
One of the best serums for dry sensitive skin.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent suitability for your dry and sensitive skin as Glycerin and Sodium Hyaluronate provide superior hydration and humectant action, ideal for combating dryness and flakiness.
- The high concentrations of Rh-Oligopeptide-1 and Barley Sh-Oligopeptide-1 further enhance skin regeneration, plumping fine lines and wrinkles for a smoother appearance.
- The product is safe for your skin, containing no harsh ingredients and featuring soothing components that minimize irritation risk.
How to apply
- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
People Say
★4.7Overall rating based on 600+ reviewsUsers with dry, mature, or dehydrated skin highly praise this serum for its deep hydration, plumping effects, and ability to reduce fine lines, resulting in a radiant complexion. Some users with oily or combination skin find the texture sticky or heavy.
Highlights
Hydrating and plumping Mostly Mentioned
- “Gives the skin an instant hydration boost! It's also great for plumping up the skin.”
- “It felt hydrating and plumping.”
- “Keeps my skin hydrated and plump.”
- “Thrilled with the glow and how well moisturized and smooth my skin looks.”
Radiant glow Often Mentioned
- “Gives my 62-year-old skin a beautiful glow!”
- “Skin looks radiant and is more resilient.”
- “Complexion has never looked more radiant or even-toned.”
- “As soon as the serum penetrates my skin, you can see the glow immediately.”
Reduces fine lines Often Mentioned
- “Visible minimizing effect on lines.”
- “Reduces the appearance of fine lines.”
- “Deep wrinkle under my eye that has pretty much disappeared!”
- “Visible improvement in the lines on my forehead.”
Expensive product Often Mentioned
- “Pity that it's so expensive, I'd definitely repurchase.”
- “Not the best for this price.”
- “Yes, it's an expensive product.”
- “Definitely an investment purchase.”
Improves texture Sometimes Noted
- “Skin looks more plumped, smooth and hydrated.”
- “Real difference in the texture of skin.”
- “Plumper, smoother and I can get away with minimal makeup.”
- “Makes my skin look so much smoother, even-toned and brighter.”
Sticky texture Sometimes Noted
- “It feels a bit sticky on the skin.”
- “Can still feel sticky on my skin.”
- “It feels like a film on my skin.”
- “Not absorbing during the night.”
Too heavy Rarely Noted
- “Might be too much for some skin types, especially during the warmer weather.”
- “Almost a little oily.”
- “I put it in the evening and it is not absorbing.”
Sources: lovi.care, dermstore.com, cultbeauty.com, bioeffect.com, beauty-detective.com, whowhatwear.com, and more
Questions and answers
What makes BIOEFFECT EGF Serum one of the best fits for dry sensitive skin?
This serum is one of the best fits because glycerin and sodium hyaluronate provide deep hydration to combat dryness and flakiness on dry sensitive skin. It also contains high concentrations of skin-regenerating ingredients that help plump fine lines for a smoother look while keeping irritation risk low.
Which ingredients make this serum a good fit for dry sensitive skin?
Glycerin and Sodium Hyaluronate make this serum a great fit by providing deep hydration to fight dryness and flakiness, while soothing components help keep your skin calm and comfortable.
What does EGF do for dry sensitive skin?
EGF helps calm dry sensitive skin by supporting skin repair and renewal, though it may need to be paired with rich moisturizers and soothing ingredients to properly comfort very dry or reactive areas.
What does Glycerin do for dry sensitive skin?
Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008
Where does this serum go in a skincare routine for dry sensitive skin?
This serum goes in the evening routine after your cleansing and toning steps, followed by a moisturizer. Applying treatments at night helps keep things simple and provides extra safety around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first to help keep your dry, sensitive skin calm and hydrated before layering retinol on top. This approach helps reduce the likelihood of irritation while supporting skin regeneration and a smooth feel.
How often should I use this serum?
This treatment is used in the evening as part of your routine. It helps keep dry and sensitive skin calm and hydrated without harsh ingredients.
Can this serum clog pores, cause breakouts or purging for dry sensitive skin?
This serum is unlikely to clog pores or cause breakouts on dry sensitive skin, as it contains no harsh ingredients and features a safe formula designed to minimize irritation. Its hydrating and soothing components help keep skin comfortable without heavy oils that typically trigger blemishes.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Lidocaine at 20% and lidocaine 10% with trometamol provided effective pain control comparable to lidocaine/prilocaine in healthy adults after a 60-minute exposure, while propylene glycol did not accelerate the onset of analgesia.
Journal of Pain Research, 2017A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks.
Journal of Cosmetic Dermatology, 2020Ketorolac tromethamine poloxamer hydrogel provided sufficient bioavailability to reach the site of action with anti-inflammatory efficacy and no visual skin irritation in volunteers.
Pharmaceutical Research, 2017
Ingredients
Glycerin, Water, Sodium Hyaluronate, Tromethamine, Sodium Chloride, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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