Bioderma vs Clinique
Bioderma and Clinique are renowned skincare houses that offer thoughtful ranges of moisturizers, serums, and makeup removers designed to support healthy complexions. The French brand is known for gentle moisturizers, soothing makeup removers, targeted serums, and purifying cleansers enriched with glycerin, suiting acne-prone and oily acne-prone skin best through formulations like Sensibio Gel Moussant, Sensibio Micellar Cleansing Oil, and Atoderm Intensive Eye. Conversely, the American house is widely loved for its moisturizers, serums, makeup removers, and eye products incorporating hyaluronic acid, glycerin, and caffeine, catering primarily to dry sensitive and oily skin with solutions such as Clarifying Do-Over Peel, for Men Oil-Free Moisturizer, and Smart Clinical Repair Lifting Face + Neck Cream. While both brands rely on glycerin to improve skin hydration and restore barrier function, they differ in their heritage, founding dates, and specific ingredient profiles like hyaluronic acid and caffeine.
Bioderma is a French skincare brand founded in 1977 and owned by Jean-Noël Thorel Foundation since 2018.
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
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This page compares some of the most popular Bioderma and Clinique products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Bioderma vs Clinique products
People Say
Gentle and Non-Irritating Mostly MentionedMostly Mentioned
- “doesn't sting my eyes — Bioderma Sensibio H2O”
- “doesn't cause any irritation — Bioderma Sensibio Micellar Cleansing Oil”
- “mildest face wash I've tried — Bioderma Sensibio Gel Moussant”
- “never irritated my eyes — Clinique All About Eyes”
Hydration and Moisturizing Often MentionedMostly Mentioned
- “healed my dry skin — Bioderma Sébium Hydra”
- “skin feels plump — Bioderma Atoderm Crème Ultra”
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- “skin feels soft and smooth — Clinique Moisture Surge Overnight Mask”
Texture and Absorption Often MentionedMostly Mentioned
- “sinks in immediately — Clinique moisture surge”
- “sinks in instantly — Clinique Dramatically Different Moisturizing Gel”
- “Absorbs quickly without feeling sticky — Clinique Dramatically Different Moisturizing Lotion+”
- “absorbs instantly — Bioderma Hydrabio Serum”
Makeup Base and Compatibility Sometimes NotedOften Mentioned
- “Foundation didn't settle into pores — Bioderma Sébium Pore Refiner”
- “Noticeable difference in size of pores — Bioderma Sébium Pore Refiner”
- “foundation glides on — Clinique moisture surge”
- “holds concealer in place — Clinique All About Eyes”
Cleansing and Makeup Removal Sometimes NotedSometimes Noted
- “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm”
- “Skin feels squeaky clean — Clinique Clarifying Lotion 2”
- “squeaky clean — Clinique all about clean”
- “melts every bit of make up and SPF off — Bioderma Sensibio Micellar Cleansing Oil”
Exfoliation and Skin Smoothing Not notedOften Mentioned
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “gentle enough for everyday — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “You will see the dirt with one wipe — Clinique Clarifying Lotion 2”
Price and Value Sometimes NotedOften Mentioned
- “pricier than other brands — Bioderma Sensibio Gel Moussant”
- “finished too quickly — Bioderma Hydrabio Serum”
- “pricey for water — Bioderma Sensibio H2O”
- “jar is too small for the cost — Clinique moisture surge”
Drying and Dehydration Sometimes NotedOften Mentioned
- “Skin looks like sandpaper — Bioderma Sébium Pore Refiner”
- “It isn't a cleanser I can use every day... it can be very drying. — Bioderma Sébium Gel moussant”
- “dried out my skin — Bioderma Sensibio H2O”
- “skin felt tight — Clinique Dramatically Different Moisturizing Gel”
Residue and Finish Issues Sometimes NotedSometimes Noted
- “hard to rinse off — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “feels sticky to the touch — Clinique moisture surge”
- “Left an oily film on my T-zone — Clinique Dramatically Different Moisturizing Lotion+”
- “requires a thorough follow-up — Bioderma Sensibio Micellar Cleansing Oil”
Bioderma vs Clinique routines for dry skin
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Cleanser
Atoderm Huile de Douche
Morning · Evening · Once a week
€18.35
-
Hydrating Toner
Hydrabio Serum
Morning
€27.97
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Moisturizer
Atoderm Crème Ultra
Morning · Evening · Once a week
€30.95
-
SPF
Purito Daily Soft Touch Sunscreen
Morning
€12.98
-
Pre-Cleanser
Sensibio Micellar Cleansing Oil
Evening · Once a week
€21.30
-
Serum or Treatment
Pigmentbio Sensitive Areas
Evening · Once a week
€39.70
-
Nourishing Mask
Anua Heartleaf 77% Soothing Sheet Mask
Once a week
€19.90
-
Cleanser
all about clean
Morning · Evening · Once a week
€28.05
-
Hydrating Toner
COSRX Propolis Synergy Toner
Morning
€18.55
-
Moisturizer
Smart Clinical Repair Lifting Face + Neck Cream
Morning · Evening · Once a week
€94.95
-
SPF
Purito Daily Soft Touch Sunscreen
Morning
€12.98
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€25.90
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€87.95
-
Nourishing Mask
Moisture Surge Overnight Mask
Once a week
€26.95
Bioderma vs Clinique routines for oily skin
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Cleanser
Sébium Gel moussant
Morning · Evening · Once a week
€19.50
-
Hydrating Toner
Hydrabio Serum
Morning · Once a week
€27.97
-
Moisturizer
Sébium Mat Control
Morning · Evening · Once a week
€18.45
-
SPF
make p:rem UV Defense Me Blue Ray Sun Cream
Morning
€34.30
-
Pre-Cleanser
Sensibio Micellar Cleansing Oil
Evening · Once a week
€21.30
-
Cleansing Toner
Pixi Glow Tonic
Evening
€29.29
-
Serum or Treatment
Pigmentbio Sensitive Areas
Evening · Once a week
€39.70
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
-
Cleanser
Redness Solutions Soothing Cleanser
Morning · Evening · Once a week
€31.05
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.99
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€30.25
-
SPF
make p:rem UV Defense Me Blue Ray Sun Cream
Morning
€34.30
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€25.90
-
Cleansing Toner
Clarifying Lotion 2
Evening
€47.15
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
Bioderma vs Clinique routines for combination skin
-
Cleanser
Sébium Gel moussant
Morning · Evening · Once a week
€19.50
-
Hydrating Toner
Sébium Lotion
Morning · Once a week
€20.90
-
Moisturizer
Sébium Mat Control
Morning · Evening · Once a week
€18.45
-
Pre-Cleanser
Sensibio Micellar Cleansing Oil
Evening · Once a week
€21.30
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€17.15
-
Serum or Treatment
Pigmentbio Sensitive Areas
Evening · Once a week
€39.70
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
-
Cleanser
all about clean
Morning · Evening · Once a week
€28.05
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€30.25
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€25.90
-
Cleansing Toner
Clarifying Lotion 2
Evening
€47.15
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
Questions and answers
Bioderma or Clinique: which is better?
Bioderma is better for acne-prone, dry, and combination skin, where Lovi fit levels reach High compared to Clinique's Average. Clinique is 100 percent fragrance-free across the products on this page, whereas Bioderma includes fragrance in some items. Hyaluronic acid helps hydrate the skin in Clinique products.
What is the difference between Bioderma and Clinique?
Bioderma and Clinique are both popular skincare brands, but they differ in formulation and performance. Bioderma excels in gentle, soothing products for acne-prone skin, while Clinique is known for lightweight, oil-controlling moisturizers and advanced cleansing options. Clinique is also entirely fragrance-free across its products on this page, whereas some Bioderma products include fragrance.
Bioderma or Clinique for dry skin?
Bioderma has a High routine fit for dry skin, whereas Clinique has an Average routine fit. Reviewers note that Bioderma is particularly good for soothing and barrier-repairing moisturizers.
Bioderma or Clinique: which cleanser is better?
Clinique is better for cleansing and makeup removal overall. Reviewers note that Clinique offers gentle and effective cleansers and deeply dissolving makeup removers, and the products on this page outperform Bioderma in cleansing and makeup removal.
Which is more affordable, Bioderma or Clinique?
Bioderma is more affordable as price and value are better rated for Bioderma on the page.
Bioderma or Clinique: which has better fragrance-free options?
Clinique is better for fragrance-free options because every product on its page lists no fragrance. In contrast, Bioderma includes fragrance in some of its products on this page.
Bioderma or Clinique: which offers better texture and absorption?
Clinique offers better texture and absorption compared to Bioderma. Reviewers frequently note that Clinique provides lightweight and fast-absorbing moisturizers, whereas Bioderma can sometimes present texture and finish issues like stickiness or greasiness.
Bioderma or Clinique for oily skin?
Bioderma and Clinique are both a High fit for oily skin. Clinique features fragrance-free products on this page, while Bioderma offers a targeted range that includes key ingredients like glycerin.
Bioderma or Clinique: which moisturizer is better?
Bioderma offers soothing and barrier-repairing moisturizers that fit dry skin at a High level, while Clinique features hydrating and fast-absorbing moisturizers with every product listing no fragrance.
Bioderma or Clinique for sensitive skin?
Bioderma has a High fit for sensitive skin, while Clinique also has a High fit for sensitive skin on the products on this page. Bioderma excels in gentle and non-irritating care, whereas Clinique is known for fragrance-free formulations.
Bioderma or Clinique for acne-prone skin?
Bioderma has a High routine fit for acne-prone skin, whereas Clinique has an Average routine fit. Reviewers note that Bioderma offers soothing and barrier-repairing moisturizers along with gentle cleansers.
Bioderma or Clinique for mature skin?
For mature skin, Lovi rates Bioderma with a High routine fit and Clinique with a High routine fit as well. Bioderma features soothing and barrier-repairing moisturizers with key ingredients like glycerin, while Clinique relies on fragrance-free options containing hyaluronic acid and caffeine.
Dermatologic Therapy, 2022Skin Pharmacology and Physiology, 2013
Research behind their key ingredients
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Hesperidin, Hesperetin, Rutinose, and Rhamnose Act as Skin Anti-Aging Agents
Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy
Effect of topically applied lipids on surfactant-irritated skin
Potentially beneficial effects of rhamnose on skin ageing: an in vitro and in vivo study
Formulation strategies to modulate the topical delivery of anti-inflammatory compounds
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Salicyloyl-phytosphingosine: a novel agent for the repair of photoaged skin
Algae extract protection effect on oxidized protein level in human stratum corneum
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Interest in Micellar Solution to Reduce Unpleasant Skin Sensations
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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