Bayer vs NEOCUTIS

Questions and answers

Research behind their key ingredients

• Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

  Hyaluronic acid · Dermatologic Therapy, 2022

• Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin

  Squalane · Scientific Reports, 2020

• Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris

  Azelaic acid · Pharmaceutics, 2021

• The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study

  Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017

• Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications

  Palmitoyl tripeptide-1 acetate, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015

• Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris

  Azelaic acid · Dermatology and Therapy, 2024

• The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study

  Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023

• Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast

  Squalane · Molecules, 2025

• Influence of vitamin E acetate on stratum corneum hydration

  Tocopheryl acetate · Arzneimittel-Forschung, 1998

• Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy

  Tocopheryl acetate · Scientific Reports, 2025

• Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism

  Palmitoyl tripeptide-1 acetate, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

• Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking

  Palmitoyl tripeptide-1 acetate · International Journal of Cosmetic Science, 2026

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.