glymed+ Oxygen Cream for combination skin
Hydrolyzed Candida Saitoana Extract
Lactobacillus Wasabia Extract
Tetrahexyldecyl Ascorbate
Glycerin
Tocopheryl Acetate
Average
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for combination skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration for your combination skin, as glycerin and sorbitol provide excellent moisturizing effects to plump and hydrate the skin. Tropaeolum Majus Stem Extract also aids in potential seboregulation, which is beneficial for managing oily shine.
- While the formula provides general skincare benefits, it lacks specialized ingredients to directly target concerns like oily shine.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
Questions and answers
How well does GlyMed Plus Oxygen Cream work for combination skin?
GlyMed Plus Oxygen Cream works moderately well for combination skin, offering basic hydration and safety from irritation without targeting oily shine as effectively as top-rated options. To better suit combination skin, a moisturizer of this type needs specialized ingredients that directly control excess oil while delivering balanced hydration.
Which ingredients make this cream a good fit for combination skin?
Glycerin and sorbitol help make this cream a good fit for combination skin by drawing in moisture to plump and hydrate dry areas. To better suit this skin type, a product of this type needs brightening and soothing ingredients that directly target and reduce oily shine.
What does Hydrolyzed Candida Saitoana Extract do for combination skin?
Hydrolyzed Candida Saitoana Extract helps combination skin look clearer and more balanced by supporting the skin's natural renewal process. It works to smooth out rough patches while keeping oily areas feeling fresh and refined.
What does Lactobacillus Wasabia Extract do for combination skin?
Lactobacillus Wasabia Extract helps keep combination skin smooth and balanced while providing strong antioxidant protection. Because it helps fight enzymes that break down skin firmness, it is a great addition to an anti-aging routine.
Where does this cream go in a skincare routine for combination skin?
This cream fits into a combination skin routine as a moisturizing treatment used in the evening and during weekly care steps, or as a daytime moisturizer. It is unlikely to cause irritation because it lacks harsh ingredients, but combination skin also needs specialized ingredients to directly target concerns like oily shine.
Can I use this cream with retinol, and in what order?
You can use this cream in the evening along with retinol, applying it after your retinol treatment to help keep your skin comfortable and hydrated. Combination skin also needs ingredients like niacinamide or clay to help control oily shine better.
How often should I use this cream?
You can use this moisturizing treatment daily to help keep your combination skin soft and hydrated. Twice-daily application is unlikely to cause irritation and may improve overall skin texture and moisture.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for combination skin?
This cream is unlikely to clog pores or cause breakouts on combination skin. It has a safe profile with no harsh ingredients, though a product for this skin also needs specialized ingredients to directly target oily shine.
Can I use this cream around the eyes or on my body?
This moisturizing treatment is safe to use around the eyes and on the body, as it has a very safe profile with no harsh ingredients. However, because the skin on the body and around the eyes is very thin, a product of this type needs extra soothing and strengthening ingredients to truly benefit those delicate areas.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Exogenous sorbitol protected epidermal keratinocytes from osmotic toxicity in vitro and significantly improved skin barrier repair and moisturization in individuals in arid environments.
Journal of Cosmetic Science, 2013A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Isosaponarin isolated from wasabi leaf increased type I collagen production in human fibroblasts by up-regulating TbetaR-II and P4H expression.
Journal of Natural Medicines, 2010Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Isodecyl Neopentanoate, Isononyl Isononanoate, Glycerin, Tropaeolum Majus Stem Extract, Polyacrylate Crosspolymer-6, Hydroxystearyl Glucoside, Hydrolyzed Candida Saitoana Extract, Sorbitol, Lactobacillus Wasabia Extract, Sake Extract, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Hydroxystearyl Alcohol, Grapefruit Peel Oil, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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