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glymed+ Oxygen Cream for acne-prone skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

glymed+ Oxygen Cream

Average

  • HighCombination Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for acne-prone skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate hydration for your combination skin, as glycerin and Tropaeolum Majus Stem Extract provide humectant and barrier-enhancing benefits, though these are not specifically targeted for acne, blemishes, and breakouts.
  • Hydrolyzed Candida Saitoana Extract and sake extract offer additional barrier support and general skin conditioning, which are beneficial but do not directly address your primary concerns.
  • The product is safe for your acne-prone skin, with grapefruit peel oil and tocopheryl acetate providing soothing effects and no harsh or prohibited ingredients.

How to apply

  • Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
  • Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
  • Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
  • Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
  • Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.

Questions and answers

How well does GlyMed Plus Oxygen Cream work for acne-prone skin?

GlyMed Plus Oxygen Cream works reasonably well for acne-prone skin, providing moderate hydration and soothing effects through ingredients like glycerin and tocopheryl acetate, though it does not specifically target breakouts. A moisturizing treatment for this skin needs ingredients that directly address acne and blemishes while supporting hydration without irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017Contemporary Clinical Trials Communications, 2021

Which ingredients make this cream a good fit for acne-prone skin?

Glycerin, grapefruit peel oil, and tocopheryl acetate make this cream a safe fit by providing moderate hydration and soothing effects without harsh ingredients. However, because it lacks targeted ingredients for blemishes and breakouts, a product for this skin needs effective acne-fighting ingredients, soothing extracts, and lightweight hydrators that balance oil without causing irritation.

Contemporary Clinical Trials Communications, 2021

What does Hydrolyzed Candida Saitoana Extract do for acne-prone skin?

Hydrolyzed Candida Saitoana Extract helps improve the look of acne-prone skin by supporting a clear and smooth texture. It is generally well-tolerated and may help keep pores from clogging, leaving your face feeling balanced.

What does Lactobacillus Wasabia Extract do for acne-prone skin?

Lactobacillus Wasabia Extract helps calm acne-prone skin by soothing redness and balancing surface bacteria. This ingredient is unlikely to clog pores and works well to keep oily skin clear and smooth.

Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in your evening routine after cleansing and before your final moisturizer, or as your main moisturizer in the morning. Acne-prone skin works best with products that provide lightweight hydration while actively targeting breakouts and blemishes.

Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying your retinol first, letting it absorb, and then following with the cream to help keep your skin soft while soothing potential irritation. Using a barrier-supporting moisturizer alongside retinol helps improve your skin recovery and overall treatment comfort.

Cutis, 2006

How often should I use this cream?

You can use this moisturizing treatment daily to help keep your skin soft and calm. For an average fit on acne-prone skin, a product of this type needs targeted blemish-fighting ingredients and oil-balancing actives to properly address breakouts.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts on acne-prone skin, as it contains soothing ingredients with a safe profile and no harsh additives. However, because it only offers moderate hydration without ingredients specifically targeted for blemishes and breakouts, acne-prone skin usually needs a moisturizing treatment with blemish-fighting ingredients and oil-balancing benefits.

Contemporary Clinical Trials Communications, 2021

Can I use this cream around the eyes or on my body?

This cream is safe to use on the body and around the eyes, as its soothing ingredients help condition the skin without causing irritation. However, acne-prone skin needs products with targeted ingredients that directly clear breakouts and blemishes.

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.

    Contemporary Clinical Trials Communications, 2021

  • Isosaponarin isolated from wasabi leaf increased type I collagen production in human fibroblasts by up-regulating TbetaR-II and P4H expression.

    Journal of Natural Medicines, 2010

  • Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

    Experimental Dermatology, 2003

  • Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

    Journal of Periodontology, 2009

  • Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

    Journal of Cosmetic Dermatology, 2022

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.

    Journal of Cosmetic Dermatology, 2025

  • Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.

    Journal of Cosmetic Dermatology, 2024

  • A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.

    Journal of Cosmetic Dermatology, 2022

Why other moisturizers fit acne-prone skin better

Ingredients

Water, Isodecyl Neopentanoate, Isononyl Isononanoate, Glycerin, Tropaeolum Majus Stem Extract, Polyacrylate Crosspolymer-6, Hydroxystearyl Glucoside, Hydrolyzed Candida Saitoana Extract, Sorbitol, Lactobacillus Wasabia Extract, Sake Extract, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Hydroxystearyl Alcohol, Grapefruit Peel Oil, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
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