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Hexapeptide and magnesium

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Hexapeptide and magnesium: keep them apart

Keep them apart

Use them at different times of day, applying the peptide serum in the morning and the magnesium at night, because they cancel each other out. Combining these two ingredients stops them from working properly on your skin, so you will not see the results you want. You can easily fix this by using one in your morning routine and the other at night.

Hexapeptide products

Magnesium products

Questions and answers

Can you use hexapeptide and magnesium together?

Keep hexapeptide and magnesium apart in your routine because unchelated metal ions like magnesium may complex with peptides and reduce their biological activity.

Which goes first, hexapeptide or magnesium?

Keep hexapeptide and magnesium apart because unchelated metal ions may complex with peptides and reduce their biological activity. Use them in separate routines to avoid interactions.

Are hexapeptide and magnesium good for sensitive skin?

Keep hexapeptide and magnesium apart in your routine because they may form inactive complexes that reduce their biological activity.

Research on hexapeptide and magnesium

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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