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Glycolic acid and niacinamide

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Glycolic acid and niacinamide: depends on the strength

Depends on the strength

Use them at different times of day with niacinamide in the morning and glycolic acid at night, because strong acids can clash with niacinamide. Mixing them can cause temporary redness and stinging on your skin. You can switch to a gentler product strength or wait at least thirty minutes between applying them.

Niacinamide: A B vitamin that improves aging facial skin appearanceThe effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer

Glycolic acid products

Niacinamide products

Questions and answers

Can you use glycolic acid and niacinamide together?

Using glycolic acid and niacinamide together depends on the strength because strong acids can convert niacinamide and cause flushing and irritation. You can safely use them by separating the ingredients by at least 30 minutes or using them in different routines such as morning and night.

Which goes first, glycolic acid or niacinamide?

Glycolic acid and niacinamide should be separated by at least thirty minutes or used in different routines because strong acids can cause flushing and irritation when combined with niacinamide. Products like Rodial SUPER ACIDS X-TREME HANGOVER MASK and COSRX AHA 7 Whitehead Power Liquid contain both ingredients, so using them at different times of day helps prevent overloading sensitive skin.

Are glycolic acid and niacinamide good for sensitive skin?

Glycolic acid and niacinamide may not be suitable for sensitive skin depending on the strength, because strong glycolic acid can convert niacinamide and cause flushing and irritation. To avoid this, you can separate them by at least 30 minutes or use them in different routines such as AM and PM. Products like Rodial SUPER ACIDS X-TREME HANGOVER MASK and COSRX AHA 7 Whitehead Power Liquid contain both ingredients.

Research on glycolic acid and niacinamide

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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