Neostrata Triple Firming Neck Cream for acne-prone skin

Questions and answers

What the research says

• Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

  Journal of Cosmetic Dermatology, 2026

• A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

  Journal of Cosmetic Dermatology, 2015

• Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

  International Journal of Cosmetic Science, 2026

• Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants.

  Journal of Cosmetic and Laser Therapy, 2019

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks.

  International Journal of Dermatology, 2000

• Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone.

  Dermatologic Surgery, 2017

• Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide.

  Journal of Cosmetic Dermatology, 2007

• N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers.

  Advanced Pharmaceutical Bulletin, 2016

• Liposomes containing N-acetyl glucosamine prepared using the fusion method significantly increased skin moisture content compared to empty liposomes in human volunteers over a 5-hour period.

  Journal of Cosmetic Dermatology, 2013

Why other products fit acne-prone skin better

• A 30% supramolecular salicylic acid peel improved the global acne grading score and skin barrier indicators, decreased cutaneous microbiome richness and evenness along with Staphylococcus proportion, reduced inflammatory cytokines, and increased caveolin-1 expression in 28 patients with moderate-to-severe acne vulgaris.

  Dermatology and Therapy, 2023

• Treatment with 45% mandelic acid peel showed nearly equal overall efficacy as 30% salicylic acid peel in patients with mild-to-moderate facial acne vulgaris, but with fewer adverse effects.

  Journal of Cosmetic Dermatology, 2020

• A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face.

  Giornale Italiano Di Dermatologia E Venereologia, 2015

Ingredients

Water, Cyclopentasiloxane, Glycerin, Dimethicone, Acetyl Glucosamine, Cetearyl Alcohol, Glycolic Acid, Gluconolactone, Peg-100 Stearate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Caffeine, Hyaluronic Acid, Tocopherol Vitamin E Acetate, Caprylyl Glycol, Phenoxyethanol, Chlorphenesin, Xanthan Gum, Disodium Edta

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.