Medicube Red Serum for oily skin
Salicylic Acid
Centella Asiatica Extract
Oil Tree Leaf
Sophora Angustifolia Root Extract
Lavandula Angustifolia Lavender WaterSuperior
- SuperiorOily Skin Fit
- HighEffectiveness
- ExcellentSafety
One of the best serums for oily skin.
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent treatment for your oily, acne-prone skin as salicylic acid and colloidal sulfur work synergistically to deeply exfoliate and control sebum production, effectively reducing acne lesions and shine.
- Centella Asiatica Extract and Chamomilla Recutita Flower Extract provide significant soothing benefits, complementing the active ingredients and enhancing overall skin comfort.
- The formulation is safe for your skin, with no harsh ingredients and a focus on calming components that minimize irritation risk.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
People Say
★4.2Overall rating based on 100+ reviewsBased on limited data, users with acne-prone and sensitive skin find this serum effective at calming redness and providing deep hydration without greasiness. Many users appreciate its ability to soothe inflammation and control sebum. However, opinions on its effectiveness in reducing active acne are divided, with some experiencing significant clearing and others seeing minimal improvement.
Highlights
Hydrating, lightweight Often Mentioned
- “lightweight, non greasy”
- “deep hydration”
- “absorbs well”
- “moisturizing effect”
Soothes redness Often Mentioned
- “reduced my redness”
- “calming effect”
- “calm down within minutes”
- “soothe irritated skin”
Small quantity Often Mentioned
- “price is quite expensive for 30mls”
- “quantity is disappointingly small”
- “runs out much faster”
- “pricey”
Strong medicinal scent Often Mentioned
- “smell is a bit strong”
- “medicinal smell”
- “tea tree scent is overpowering”
- “smells like clay”
Controls acne Sometimes Noted
- “helped with my acne”
- “reduced small bumps”
- “controls sebum production”
- “prevent new ones”
Non-sticky finish Sometimes Noted
- “not sticky”
- “absorbs quickly”
- “leaves skin soft”
- “no tackiness”
Faulty dispenser Sometimes Noted
- “shoots out suddenly”
- “splatters everywhere”
- “dispense... too forcefully”
- “hard to control”
Mixed acne results Rarely Noted
- “didn't make a difference”
- “just okay”
- “not sure if it's actually helping”
- “no dramatic improvements”
Sources: lovi.care, medicube.us, oliveyoung.com, gopicky.com, yesstyle.com, stylekorean.com, and more
Questions and answers
What makes Medicube Red Serum one of the best fits for oily skin?
Medicube Red Serum is an exceptional fit for oily skin because salicylic acid and colloidal sulfur work together to deeply exfoliate and control excess oil, which helps reduce shine and acne breakouts. Additionally, ingredients like centella asiatica extract and chamomile calm the skin to maintain comfort while keeping irritation unlikely.
Indian Journal of Pharmaceutical Sciences, 2016Journal of Cosmetic Dermatology, 2024
Which ingredients make this serum a good fit for oily skin?
Salicylic acid and colloidal sulfur make this serum a great fit by deeply exfoliating and helping control excess shine and acne. Centella asiatica extract and chamomile further support this by calming the skin and keeping it comfortable.
Journal of Cosmetic Dermatology, 2024Indian Journal of Pharmaceutical Sciences, 2016
What does Salicylic Acid do for oily skin?
Salicylic acid helps oily skin by reducing excess oil and keeping pores clear. It may also improve overall skin hydration while managing breakouts.
Journal of Cosmetic Dermatology, 2025Experimental Dermatology, 2019
What does Centella Asiatica Extract do for oily skin?
Centella Asiatica Extract helps calm redness and keeps oily skin feeling balanced by soothing irritation and supporting moisture levels. It is unlikely to feel heavy, and products of this type for oily skin need ingredients that control excess shine while maintaining hydration.
Indian Journal of Pharmaceutical Sciences, 2016Molecules, 2023
Where does it go in a skincare routine for oily skin?
This treatment goes in your evening routine, applied after cleansing and before your moisturizer. You can start using it once a week, and if your skin tolerates it well and sees good results, you may carefully use it more often.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying them on alternate nights or spacing them out to keep your skin calm and comfortable, because combining strong exfoliating acids and retinoids at the same time may easily lead to dryness or irritation. When introducing both into your routine, apply your retinol first on certain nights and this treatment on others, always following up with a gentle moisturizer.
How often should I use it?
Use this treatment in your evening routine, starting just once a week to see how your skin tolerates it. If your skin feels comfortable and you see good results, you can carefully use it more often.
Can this serum clog pores, cause breakouts or purging for oily skin?
This serum is unlikely to clog pores or cause breakouts on oily skin, as salicylic acid and colloidal sulfur help clear dead skin and control shine while keeping irritation low. Reviewers note mixed acne results, but the gentle formulation focuses on calming ingredients to support clear skin safely.
Journal of Cosmetic Dermatology, 2024Journal of Drugs in Dermatology, 2023
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.
Journal of Cosmetic Dermatology, 2024The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle.
Journal of Drugs in Dermatology, 2023Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023Combining azelaic acid and matrine in dissolving microneedles at a 1:1 molar ratio achieved higher skin permeability, synergistic antibacterial rates above 95%, and no skin irritation compared to commercially available azelaic acid gel.
European Journal of Pharmaceutical Sciences, 2021Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.
CMAJ, 2010A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.
BioMed Research International, 2020Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.
Journal of Cosmetic Dermatology, 2024Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical herbal treatments including lemon balm, olive leaf extract, propolis, and sage-rhubarb cream reduce pain, swelling, lesion size, and healing time in patients with herpes labialis compared with placebo or acyclovir.
Journal of Integrative and Complementary Medicine, 2025Topical oleuropein formulations reduced erythema, transepidermal water loss, and blood flow by approximately 22%, 35%, and 30% in healthy volunteers with UVB-induced erythema.
International Journal of Cosmetic Science, 2008An oil-in-serum formulation containing olive extract standardized in hydroxytyrosol improved skin barrier function and significantly reduced hyperpigmentation in participants with post-inflammatory hyperpigmentation after 45 days of application.
AAPS PharmSciTech, 2026Co-amorphous salt of ursodeoxycholic acid and matrine incorporated into dissolving microneedles enhanced aqueous solubility, skin permeation, growth-inhibitory effects against Cutibacterium acnes, and anti-inflammatory activity compared to single-component groups and topical gel in a murine acne model.
International Journal of Pharmaceutics, 2026Lavandula angustifolia leaf callus extract enhanced skin cell viability, reduced oxidative stress and melanin content, improved wound healing, and enhanced skin barrier function in human skin cells and clinical tests.
Free Radical Biology & Medicine, 2025Tea tree oil effectively treated acne while lavender and rosemary oils demonstrated anti-inflammatory and anti-aging properties in derma cosmetic applications based on an evaluation of various essential oils.
Frontiers in Medicine, 2025A blend of Lavandula angustifolia flower extract and dipeptide-4 reduced oxidative and glycation markers, enhanced ATP, SOD, autophagy, and melatonin production, and improved tissue morphology in human skin models and fibroblasts.
International Journal of Cosmetic Science, 2026
Ingredients
C12-14 Pareth-12, C13-14 Isoparaffin, Sophora Angustifolia Root Extract, Camellia Japonica Leaf Extract, Dimethicone Vinyl Dimethicone Crosspolymer, Disodium Edta, Dipotassium Glycyrrhizate, Dipropylene Glycol, Lavandula Angustifolia Lavender Water, Portulaca Oleracea Extract, Betaine, Centella Asiatica Extract, Borago Officinalis Extract, Zingiber Officinale Root Extract, Sorbitol, Centaurea Cyanus Flower Extract, Artemisia Vulgaris Extract, Rhus Semialata Gall Extract, Polygala Tenuifolia Root Extract, Melia Azadirachta Extract, Xylitol, Water, Zanthoxylum Piperitum Fruit Extract, Chamomilla Recutita Leaf Extract Flower Matricaria Leaf Extract Flower, Carbomer, Butylene Glycol, Propylene Glycol, Salvia Sclarea Extract, Melaleuca Alternifolia Tree Oil Leaf, Salicylic Acid, Pulsatilla Koreana Extract, Willow Bark Extract, Phellodendron Amurense Bark Extract, Magnolia Obovata Bark Extract, Hyacinthus Orientalis Extract, Tocopherol Vitamin E, Rice Extract, Ci 42090, Camellia Sinensis Leaf Extract, Laureth-7, Tocopheryl Acetate Vitamin E, Peg-60 Hydrogenated Castor Oil, Peg Ppg-17 6 Copolymer, Phenoxyethanol, Polyacrylamide, Triethanolamine, Ethanolamine, Platycodon Grandiflorum Root Extract, Diethoxyethyl Succinate, Dandelion Root Extract Rhizome, Usnea Barbata Extract, Ovalicin, Grapefruit Leaf Extract, Colloidal Sulfur
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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