Hanhoo Blemish Patch for mature skin

How to apply

Questions and answers

What the research says

• Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability.

  Aesthetic Plastic Surgery, 2026

• Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation.

  Dermatologic Therapy, 2022

• Topical 5% tea tree oil gel significantly improved total acne lesions and acne severity index compared to placebo in 60 patients with mild to moderate acne vulgaris, showing 3.55 times and 5.75 times greater efficacy respectively.

  Indian Journal of Dermatology, Venereology and Leprology, 2007

• Lactobacillus-fermented Chamaecyparis obtusa reduced inflammatory acne lesions by 65.3% compared to 38.2% with tea tree oil in 34 patients over 8 weeks, demonstrating superior efficacy, faster onset, and safety.

  Dermatology, 2014

• Daily application of hydrocolloid dressing completely prevented nasogastric tube-related pressure injuries, whereas skin care interventions showed no significant preventive effect compared to the control group in intensive care unit patients.

  Journal of Tissue Viability, 2024

• Hydration of scars for 2 months resulted in significantly reduced itching, somewhat reduced pain, and increased pliability by 10% for both hydrocolloid dressing and moisturizer treatments in patients with keloids or hypertrophic scars, with no change in physical parameters.

  Dermatologic Surgery, 1996

• Adjunctive hydrocolloid dressing with 0.1% mometasone furoate cream significantly increased treatment efficacy and cost-effectiveness compared to topical steroid alone in patients with moderate to severe lichen simplex chronicus.

  Skin Health and Disease, 2023

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• Ethyl acetate and aqueous fractions of Bambusa vulgaris leaves accelerate cutaneous wound healing and inhibit carrageenan-induced paw edema in rats.

  Journal of Ayurveda and Integrative Medicine, 2016

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Tea tree oil nanoemulsion containing adapalene gel demonstrated significantly greater reductions in total, inflammatory, and non-inflammatory acne lesions as well as acne severity index compared to adapalene marketed gel in 100 patients with acne vulgaris over 12 weeks.

  Archives of Dermatological Research, 2022

• Topical tea tree oil treatment confirmed efficacy on Demodex mite blepharitis across fourteen papers evaluating chronic blepharitis compared to no treatment or alternative management.

  BioMed Research International, 2022

• Weekly treatment with tea tree oil-saturated human amniotic membrane showed superior efficacy in healing pityriasis versicolor lesions and fungicidal activity compared to daily application of 1% tioconazole cream in 120 patients.

  Cell and Tissue Banking, 2020

Ingredients

Hydrocolloid, Aloe Barbadensis Leaf Extract, Bambusa Vulgaris Extract, Hydrolyzed Hyaluronic Acid, Melaleuca Alternifolia Tree Oil Leaf

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.