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Skinfix vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Skinfix and Sesderma are distinguished skincare brands rooted in clinical efficacy, with the Canadian line established in 2014 and the Spanish laboratory operating since 1989. Skinfix is beloved for its deeply nourishing moisturizers featuring rich, restorative ingredients, making it best suited for dry and sensitive skin, whereas Sesderma is beloved for its advanced serums and botanical extracts that best suit sensitive, hyperpigmented, and aging skin types. Both offer targeted solutions, such as the Barrier+ Triple Lipid-Peptide Cream for acne-prone skin from the former and the Azelac RU Serum for similar concerns from the latter, highlighting how they differ in product delivery while sharing a commitment to a balanced complexion.

Skinfix is a Canadian skincare brand founded in 2014 and owned by Skinfix Inc..

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Skinfix and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Skinfix vs Sesderma products

Questions and answers

Skinfix or Sesderma: which is better?

Skinfix is a better fit for dry sensitive skin, as Lovi rates its products High for that skin type, whereas Sesderma rates Low. Every product on this page from Skinfix lists no fragrance, while Sesderma includes fragrance.

What is the difference between Skinfix and Sesderma?

Skinfix was founded in 2014 in Canada, whereas Sesderma was founded in 1989 in Spain. Lovi gives the products on this page for Skinfix a High fit for dry, sensitive, mature, and sensitive skin, while Sesderma earns a High fit for acne-prone skin and skin with dark spots. Additionally, every product on this page for Skinfix lists no fragrance, while Sesderma includes fragrance in its serum.

Which is more affordable, Skinfix or Sesderma?

The provided page facts do not include pricing information, so it is not possible to determine whether Skinfix or Sesderma is more affordable based on this page.

Which causes fewer breakouts, Skinfix or Sesderma?

Skinfix earns an Average fit from Lovi for oily acne-prone skin, while Sesderma receives a High fit for acne-prone skin because of its serum. Every product on the Skinfix page lists no fragrance, whereas the Sesderma serum contains fragrance.

Which brand is older, Skinfix or Sesderma, and where were they founded?

Sesderma is the older brand, having been founded in Spain in 1989, while Skinfix was founded later in Canada in 2014.

Do Skinfix products contain fragrance compared to Sesderma?

Skinfix products on this page list no fragrance in their ingredients, whereas the Sesderma product contains fragrance. Therefore, shoppers looking to avoid fragrance will find that Skinfix is the better option.

Which brand offers a moisturizer versus a serum on this page?

Skinfix offers a moisturizer on this page, while Sesderma offers a serum. Lovi gives the Skinfix moisturizer a High fit for dry and sensitive skin, and the Sesderma serum a High fit for acne-prone skin and skin with dark spots.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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