Sesderma vs Silka
Sesderma and Silka are two skincare lines offering distinct paths to daily wellness. Sesderma is known for advanced serums and engineered formulas featuring botanical extracts and active compounds, while the latter is beloved for thoughtful serums and effective formulas like the Papaya Soap for acne-prone skin. The Spanish brand suits sensitive, hyperpigmented, and aging skin types best, whereas Silka suits balanced, oily, dry, combination, and sensitive skin best. Both brands differ because the former relies on synergistic ingredients to refine skin texture and promote a radiant complexion, while its counterpart delivers gentle and reliable care for daily routines.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Sesderma and Silka products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Sesderma or Silka: which is better?
Sesderma offers a High Lovi fit for acne-prone skin and skin with dark spots with its Azelac RU Serum, while Silka provides only Average fits for those skin concerns through its Papaya Soap. Azelaic acid helps improve acne vulgaris.
What is the difference between Sesderma and Silka?
For skin with dark spots, Sesderma offers a High fit with its Azelac RU Serum, whereas Silka Papaya Soap only reaches an Average fit. Lovi rates Sesderma's Azelac RU Serum as High for acne-prone, combination, and dark spot skin types, while Silka's soap rates lower across these categories.
Which is more affordable, Sesderma or Silka?
Neither Sesderma nor Silka has pricing information provided on this page.
Which causes fewer breakouts, Sesderma or Silka?
For acne-prone skin, Lovi rates Sesderma's Azelac RU Serum as High, whereas Silka's Papaya Soap is rated Low. Azelaic acid helps treat acne vulgaris.
Which brand has been established longer, Sesderma or Silka?
Sesderma has been established longer, having been founded in Spain in 1989, whereas Silka was founded in 2001.
Do products from Sesderma or Silka contain fragrance?
Sesderma includes fragrance in its Azelac RU Serum on this page. Silka products on this page list no fragrance in their ingredients.
How does the Lovi fit level of Sesderma's Azelac RU Serum compare to Silka's Papaya Soap for acne-prone skin?
For acne-prone skin, Lovi rates Sesderma's Azelac RU Serum as High, while Silka's Papaya Soap receives a Low fit.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
