Jole vs ISDIN Isdinceutics

Questions and answers

Research behind their key ingredients

• The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer

  Niacinamide · The British Journal of Dermatology, 2002

• Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial

  Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020

• Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage

  Chrysin · Journal of Agricultural and Food Chemistry, 2011

• Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin

  Glyceryl glucoside · Skin Pharmacology and Physiology, 2012

• Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation

  Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020

• Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris

  Azelaic acid · Pharmaceutics, 2021

• The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study

  Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017

• Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide

  Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012

• Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris

  Azelaic acid · Dermatology and Therapy, 2024

• Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial

  Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022

• The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study

  Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023

• Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study

  Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026

• Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation

  Ascorbyl palmitate · Journal of Microencapsulation, 2010

• Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery

  Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022

• Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism

  Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.