Soolantra Cream for combination skin
Ivermectin
Glycerin
Dimethicone
Carbomer
Cetyl Alcohol
Low
- AverageCombination Skin Fit
- AverageEffectiveness
- ConcerningSafety
A weak match for combination skin; the serums alongside fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate treatment for inflammatory lesions due to ivermectin, which reduces inflammation and kills mites, but lacks specialized ingredients to effectively manage oily shine for your combination skin, posing risks of worsening the condition.
- Glycerin provides general skincare benefits and hydration, but insufficient ingredients are present for optimal oil control on your oily areas.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
People Say
★4.1Overall rating based on 500+ reviewsA notable portion of users experience an initial worsening of their skin, including breakouts and irritation, during the first few weeks of use before seeing improvements, indicating a need for patience.
Highlights
Clears pustules Mostly Mentioned
- “Cleared all lumps and bumps”
- “Pustules diminishing after 3 weeks”
- “Acne-type bumps completely gone”
- “No new pustules formed”
Life-changing results Often Mentioned
- “Regained my self-confidence”
- “Best thing I have ever tried”
- “Miracle cream for my face”
- “Wish I found this years ago”
Reduces redness Often Mentioned
- “Calming redness significantly”
- “Redness reduced by 90%”
- “Skin tone is finally even”
- “Helps with persistent flushing”
Initial flare-up Often Mentioned
- “Got worse before getting better”
- “Terrible breakout in first week”
- “Face erupted with whiteheads initially”
- “Skin looked awful for two weeks”
Improves texture Sometimes Noted
- “Skin feels baby soft”
- “Smoother than it has ever been”
- “Eliminated scabby, peeling skin”
- “Rough patches smoothed out”
High cost Sometimes Noted
- “Very expensive without insurance”
- “Price is too high”
- “Insurance declined coverage”
- “Cost is a major downside”
Slow onset Sometimes Noted
- “Took 3 months to see results”
- “Requires patience, not overnight”
- “Slow process to clear skin”
- “Didn't work until week 12”
Burning or itching Rarely Noted
- “Mild burning upon application”
- “Skin felt itchy and irritated”
- “Stinging sensation for first few days”
- “Face hurt when touched”
Sources: lovi.care, drugs.com, webmd.com, theindependentpharmacy.co.uk, doctorfox.co.uk, and more
Questions and answers
Why is Soolantra Cream a weak match for combination skin?
Soolantra Soolantra Cream is a weak match because it lacks specialized ingredients to effectively manage oily shine for your combination skin, posing risks of worsening the condition. A product for this skin needs ingredients like niacinamide, propolis, and zinc PCA to regulate oiliness and provide balanced hydration without excess oil.
Which ingredients make this cream a poor fit for combination skin?
This cream is a weak match for your combination skin because it lacks specialized ingredients to effectively manage oily shine while providing treatment for bumps. A product of this type needs ingredients like niacinamide, propolis, and zinc PCA to provide balanced hydration and regulate oiliness without making the skin too oily.
What does Ivermectin do for combination skin?
Ivermectin helps calm facial skin by reducing the tiny mites that can cause irritation and redness. For combination skin, it is unlikely to disrupt your routine, but you should check with a doctor to see if it fits your specific skin needs.
The Journal of Investigative Dermatology, 2025Case Reports in Dermatology, 2022
What does Glycerin do for combination skin?
Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017
Where does this cream go in a skincare routine for combination skin?
This cream goes in the evening routine after cleansing and before moisturizing, though it is a weak fit for combination skin because it lacks oil-controlling ingredients for oily areas. Combination skin needs targeted ingredients that manage oily shine without worsening the skin condition.
Can I use this cream with retinol, and in what order?
You can use this treatment alongside a retinol by applying your retinol at night and using this cream as directed in your evening routine, but this product may not be the best fit for combination skin. To properly care for combination skin, a treatment of this type needs specialized ingredients for oil control.
How often should I use this cream?
This cream is generally used once a day in the evening as a treatment step. A product for this skin type also needs specialized ingredients to manage oily shine.
Can this cream clog pores, cause breakouts or purging for combination skin?
This cream is a weak match for combination skin because it lacks specialized ingredients to effectively manage oily shine, which poses risks of worsening your skin condition. To suit combination skin, a product of this type needs specialized oil-control ingredients that balance oily areas while keeping dry patches soft and smooth.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol, stearyl alcohol, and oleyl alcohol are fatty alcohols, which soften the skin.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups.
Military Medicine, 2024A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate.
Skin Research and Technology, 2000Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms.
Clinical and Experimental Dermatology, 2007Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments.
Journal of Ocular Pharmacology and Therapeutics, 2019Incorporating nanoemulsions into hydrogels with increasing Carbopol 934 proportions from 1% to 3% progressively decreased the percutaneous flux rates of terbinafine and citral, increased drug accumulation in the stratum corneum while decreasing it in the epidermis/dermis compared to nanoemulsions alone, and shifted delivery routes from skin appendages to intercellular paths.
International Journal of Nanomedicine, 2016Topical liquiritin carbomer gel treatment restored skin barrier function, increased barrier proteins and antioxidant enzymes, and decreased inflammatory cytokines and oxidative stress in a mouse model of glucocorticoid-induced skin inflammation.
Pharmaceutics, 2024A soap-free cleansing lotion containing cetyl alcohol and sodium cocoyl apple amino acids reduced skin surface impurities and improved skin hydration, barrier function, and skin tone in 27 healthy adult subjects over 30 days.
Cureus, 2025
Why other serums fit combination skin better
Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024
Ingredients
Ivermectin, Glycerin, Isopropyl Palmitate, Carbomer, Dimethicone, Disodium Edta, Citric Acid, Cetyl Alcohol, Stearyl Alcohol, Sorbitan Stearate, Methyl Parahydroxybenzoate, Propyl Parahydroxybenzoate, Phenoxyethanol, Propylene Glycol, Oleyl Alcohol, Sodium Hydroxide, Water
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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