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Zinc

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Zinc

Zinc gently clears blemishes, calms redness, and balances oil to reveal a calm, clear complexion. It suits most skin types and is commonly available in lightweight serums. You can easily layer it with benzoyl peroxide and niacinamide, though it should be kept separate from bio-placenta peptides, hexapeptide, and acetyl hexapeptide-3.

Journal of Controlled Release, 2025The Journal of Clinical and Aesthetic Dermatology, 2020Clinical, Cosmetic and Investigational Dermatology, 2023

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Other zinc products

What to combine zinc with

IngredientTogetherHow to use them
Benzoyl peroxide Works well Use them in the same routine by applying benzoyl peroxide first, because zinc helps soothe the skin while fighting breakouts. Zinc and benzoyl peroxide
Niacinamide Works well Use them together in the same routine, applying niacinamide first and zinc second to help control excess oil and soothe skin. Zinc and niacinamide
Salicylic acid Depends Use them together in the same routine, applying salicylic acid first and zinc second to help clear blemishes. Zinc and salicylic acid
Bio-placenta peptides Keep apart Use them at different times of day, applying the zinc in the morning and the peptides at night, because combining them stops them from working. Zinc and bio-placenta peptides
Hexapeptide Keep apart Use them at different times of day, applying the peptide first and the zinc later, because mixing them makes the peptide less effective. Zinc and hexapeptide
Acetyl hexapeptide-3 Keep apart Use zinc and acetyl hexapeptide-3 at different times of day, applying zinc in the morning and the peptide at night, because they clash and cancel each other out. Zinc and acetyl hexapeptide-3
Collagen peptide Keep apart Apply zinc and collagen peptide at different times of day, using zinc in the morning and collagen peptides at night, because combining them stops them from working. Zinc and collagen peptide
Copper peptide Keep apart Use them at different times of day with copper peptide first, because mixing them directly can make the ingredients inactive. Zinc and copper peptide
Hexapeptide-9 Keep apart Apply zinc in the morning and hexapeptide-9 at night, because mixing them together makes the peptide treatment less effective. Zinc and hexapeptide-9
Peptide-rich plasma Keep apart Apply the zinc and peptide products at different times of day, using peptides in the morning and zinc at night, because combining them stops them from working. Zinc and peptide-rich plasma
Triple peptide blend Keep apart Apply the peptide serum in the morning and the zinc product at night, because mixing them makes the peptides less effective on your skin. Zinc and triple peptide blend
Palmitoyl pentapeptide-4 Keep apart Use them at different times of day with zinc in the morning and the peptide at night, because mixing them makes the peptide less effective. Zinc and palmitoyl pentapeptide-4
Palmitoyl tripeptide-1 Keep apart Apply them at different times of day with zinc in the morning and palmitoyl tripeptide-1 at night, because combining them stops them from working. Zinc and palmitoyl tripeptide-1

From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.

Questions and answers

What does zinc do for the skin?

Zinc helps soothe the skin while fighting breakouts and reducing redness. It may also help control excess oil and clear blemishes.

Journal of Controlled Release, 2025Journal of Cosmetic Dermatology, 2026

How do you use zinc?

Yes, you can use zinc in your routine, but how you apply it depends on the other ingredients you pair it with. For instance, you can use it alongside niacinamide by applying niacinamide first and zinc second to help control excess oil and soothe skin.

Should you use zinc in the morning or at night?

You can use zinc both morning and night, depending on which ingredients you pair it with. For instance, you can use it alongside niacinamide in the same routine, but you should keep it separate from bio-placenta peptides by applying zinc in the morning and the peptides at night.

Can you use zinc every day?

Yes, you can use zinc every day to help clear blemishes and soothe the skin. Daily use of products containing zinc safely reduces acne lesions and redness over time.

Journal of Controlled Release, 2025Clinical, Cosmetic and Investigational Dermatology, 2023

Does zinc cause purging or irritation?

Zinc is unlikely to cause purging, and it may help soothe the skin while fighting breakouts.

Journal of Controlled Release, 2025

Which skin types is zinc best for?

Zinc is best for blemish-prone and oily skin types, as popular products like BYOMA Clarifying Serum and Minimalist Vitamin B5 10% Moisturizer help soothe skin and control excess oil. Studies show that zinc helps reduce acne lesions and redness.

Journal of Controlled Release, 2025The Journal of Clinical and Aesthetic Dermatology, 2020

Can you use zinc with benzoyl peroxide?

Yes, you can use zinc with benzoyl peroxide in the same routine by applying benzoyl peroxide first, because zinc helps soothe the skin while fighting breakouts.

Can you use zinc with bio-placenta peptides?

You should keep zinc and bio-placenta peptides apart by using zinc in the morning and the peptides at night, because combining them stops them from working.

Research on zinc

Behind this ingredient guide

Lovi checks every ingredient with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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