SENTÉ Bio Complete Serum for combination skin
Sodium Hyaluronate
Retinol
Glycosaminoglycans
Heparan Sulfate
NiacinamideAverage
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for combination skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your combination skin, with retinol and myristoyl pentapeptide-17 effectively targeting fine lines and wrinkles by promoting collagen synthesis and antioxidant activity. Glycerin and sodium hyaluronate provide essential hydration, though they do not specifically address oily shine concerns.
- The serum is highly suitable for combination skin due to ingredients like retinol and sodium ascorbyl phosphate, which offer antioxidant protection and support collagen production.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
People Say
★4.7Overall rating based on 100+ reviewsBased on limited data, this serum is highly praised for its anti-aging effects, improving skin texture and firmness while reducing fine lines. Some users experienced a greasy feel or slow results, and a negligible number mentioned the presence of fragrance.
Highlights
Gentle formula Mostly Mentioned
- “Most tolerated retinol for my sensitive skin.”
- “Does not make my skin peel.”
- “Gentle enough for sensitive skin.”
- “No irritation at all.”
Improves texture Often Mentioned
- “Noticeable difference in my skin texture.”
- “Skin is soft and supple.”
- “Skin texture and tone are so much better.”
- “Smoother and firmer skin.”
Anti-aging benefits Sometimes Noted
- “Reduced the appearance of fine lines.”
- “Appearance is quite youthful for my age.”
- “Helped with clear discolored spots.”
- “Boosts collagen and elastin production.”
Hydrating Sometimes Noted
- “Deep hydration to prevent redness.”
- “Plenty of hydration.”
- “Keeps skin comfortably moisturized.”
Contains fragrance Rarely Noted
- “It does have fragrance.”
Greasy feel Rarely Noted
- “Very silicone based so it's really greasy feeling.”
- “Texture feels a bit heavy.”
Slow results Rarely Noted
- “Unfortunately didn't see any changes.”
- “Need more time to see benefits.”
- “Too early to speak to results.”
Sources: lovi.care, lovelyskin.com, dermstore.com, dermavenue.com, harbenhouse.com, skinelite.com, and more
Questions and answers
How well does SENTÉ Bio Complete Serum work for combination skin?
SENTÉ Bio Complete Serum works moderately well for combination skin, offering helpful hydration and smoothing fine lines with retinol, though it does not specifically target oily shine. This type of skin needs products with ingredients like niacinamide, propolis, and zinc PCA to regulate oiliness and provide balance without causing dryness.
Which ingredients make this serum a good fit for combination skin?
Retinol and sodium hyaluronate help make this serum a good fit for combination skin by smoothing fine lines and delivering hydration. To work best for this skin type, a product of this type needs ingredients like niacinamide and zinc PCA to regulate oiliness.
What does Hyaluronic Acid do for combination skin?
Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
What does Retinol do for combination skin?
Retinol helps smooth fine lines, even out skin tone, and improve firmness in combination skin. It works by encouraging faster skin renewal and boosting collagen, though it may occasionally cause mild dryness or scaling while your skin adjusts.
Where does it go in a skincare routine for combination skin?
This treatment goes in the evening routine after cleansing and before moisturizing. Combination skin needs products that also balance oily shine using ingredients like niacinamide and lightweight hydrators.
Can I use this serum with glycolic acid, and in what order?
Using this serum with glycolic acid may cause irritation because both ingredients are strong, so you should alternate them on different nights or use glycolic acid in the morning and this serum at night. When your skin needs a better fit for combination skin, a product of this type needs ingredients that balance oily shine while smoothing fine lines.
How often should I use it?
Use this serum in the evening as a treatment step, starting carefully once a week and working up if your skin tolerates it well. This routine helps you gain the anti-aging benefits of retinol while keeping your skin safe from sun irritation.
Can this serum clog pores, cause breakouts or purging for combination skin?
This serum is unlikely to cause breakouts or clog pores for your combination skin because it has an excellent safety profile without harsh ingredients. However, a product of this type needs balancing ingredients like niacinamide or lightweight hydrators to properly manage oily shine.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.
Archives of Dermatological Research, 2017Topical treatment with sphingolipids and glycosaminoglycans attenuated clinical worsening and reduced CADESI and PVAS scores compared to the untreated control group in house dust mite-allergic beagle dogs.
BMC Veterinary Research, 2020Glycosaminoglycans restored type I collagen synthesis, reduced matrix metalloproteinase-1 levels, upregulated tissue inhibitor of metalloproteinase-1, and attenuated apoptosis in tumor necrosis factor-alpha-stimulated human dermal fibroblasts by inhibiting extracellular signal-regulated kinase/activator protein-1 signaling.
International Journal of Molecular Medicine, 2018Fraction 3 of glycosaminoglycans from Liparis tessellatus eggs showed 20.1% tyrosinase inhibition at 50mg/mL and effective skin regeneration activities at 200mg/mL against skin fibroblast CCD-986sk cell lines.
International Journal of Biological Macromolecules, 2017A topical eye cream containing low molecular weight heparan sulfate and naturally derived extracts improved periorbital hyperpigmentation, fine and coarse wrinkles, puffiness, and dark circles in 15 subjects over 12 weeks.
Journal of Cosmetic Dermatology, 2019Topical low molecular weight heparan sulfate improved periorbital discoloration and wrinkles starting at week two with continuous improvement up to week 12.
Journal of Cosmetic Dermatology, 2020Topical low molecular weight heparan sulfate improved skin hydration, firmness, elasticity, barrier function, and fine lines and wrinkles in 15 patients over 8 weeks.
Journal of Drugs in Dermatology, 2015Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005
Why other serums fit combination skin better
Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Water, Butylene Glycol, Dipropylene Glycol, Cyclopentasiloxane, Peg-12 Dimethicone Crosspolymer, Dimethicone Crosspolymer, Dimethicone Vinyl Dimethicone Crosspolymer, Dimethiconol, Dimethicone, Laureth-23, Laureth-4, Glycerin, Heparan Sulfate, Pentylene Glycol, Retinyl Safflowerate, Retinol, Lysophosphatidic Acid, Myristoyl Nonapeptide-3, Myristoyl Pentapeptide-17, Ethyl Safflowerate, Ethyl Flaxseedate, Dipalmitoyl Hydroxyproline, Allantoin, Panthenol, Sodium Hyaluronate, Sodium Ascorbyl Phosphate, Alanine, Arginine Hcl, Asparagine, Aspartic Acid, Cystine, Glutamic Acid, Glutamine, Histidine Hcl, Isoleucine, Leucine, Lysine Hcl, Acetyl Methionine, Phenylalanine, Proline, Serine, Threonine, Tryptophan, Tyrosine, Valine, Calcium Pantothenate, Folic Acid, Inositol, Niacinamide, Pyridoxal Hcl, Riboflavin, Thiamine Hcl, Calcium Chloride, Magnesium Sulfate, Potassium Chloride, Sodium Chloride, Sodium Phosphate, Beta-Carotene, Polysorbate 80, Polyaminopropyl Biguanide, Tromethamine
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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