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Peter Thomas Roth PEPTIDE SKINJECTION for sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Peter Thomas Roth PEPTIDE SKINJECTION

Average

  • HighNormal Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for sensitive skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate hydration for your normal skin, as Glycerin and Hyaluronic Acid provide humectant benefits while Squalane offers emollient properties. Allantoin and Glycerin also offer soothing benefits for your redness and irritation.
  • The formula is generally safe for your sensitive skin, with no harsh ingredients and the inclusion of soothing agents like Glycerin and Allantoin.
  • This product provides basic skincare benefits such as hydration and soothing, which are supportive for your concerns.

How to apply

  • Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
  • Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
  • Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
  • You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
  • Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .

People Say

★4.6Overall rating based on 200+ reviews

This product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.

Highlights

  • Reduces fine lines Mostly Mentioned
    • “Big change in forehead lines”
    • “lines around eyes decreased”
    • “definite reduction in lines”
  • Smooths skin texture Often Mentioned
    • “Skin has never felt so smooth”
    • “makeup goes on smooth”
    • “melts into my skin”
  • Hydrating formula Sometimes Noted
    • “Thick hydrating feel”
    • “skin feels more hydrated”
    • “helps hydrate”
  • Reduces eye puffiness Sometimes Noted
    • “Less puffiness under eyes”
    • “quick relief of puffiness”
    • “noticed less puffiness”
  • Gritty serum texture Sometimes Noted
    • “Lotion has a little grit”
    • “texture is a little gritty”
    • “creamy and a bit gritty”
  • High price point Sometimes Noted
    • “hefty price”
    • “less hefty price”
  • Drying sensation Rarely Noted
    • “A bit drying”
    • “skin did not feel oily”
  • Slow/No results Rarely Noted
    • “Not noticed any reduction”
    • “only been 12 days”
    • “didn't last a week”

Sources: lovi.care, peterthomasroth.com, lovelyskin.com, dermstore.com, reddit.com, and more

Questions and answers

How well does Peter Thomas Roth Peptide Skinjection work for sensitive skin?

This moisturizing treatment is an average fit that provides moderate hydration and helps soothe redness and irritation for sensitive skin. To work best for this skin, a product of this type needs to be highly effective in soothing and hydrating while addressing concerns with no risks, rich in beneficial ingredients that maintain skin barrier function, and free of potential allergens and multiple herbal ingredients.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this moisturizing treatment a good fit for sensitive skin?

Glycerin, Hyaluronic Acid, and Allantoin help make this moisturizing treatment a good fit by offering hydration and soothing benefits for sensitive skin. This type of product needs to be highly effective in soothing and hydrating while addressing redness without irritation, and it works best when rich in ingredients that support skin barrier function.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Glycerin do for sensitive skin?

Glycerin helps keep sensitive skin soft and deeply hydrated while supporting the skin barrier. It is unlikely to cause irritation and may protect against dryness and roughness.

The British Journal of Dermatology, 2008Acta Dermato-venereologica, 1999

What does Tetrapeptide-1 do for sensitive skin?

Tetrapeptide-1 helps support skin structure and strength, making it a suitable choice for sensitive skin types. It is unlikely to cause irritation and may improve firmness while keeping the skin barrier calm.

International Journal of Cosmetic Science, 2013Polymers, 2025

Where does this moisturizing treatment go in a skincare routine for sensitive skin?

This moisturizing treatment goes in the evening routine after cleansing and toning, and before moisturizing. Sensitive skin needs a routine with gentle, calming ingredients like glycerin and allantoin to keep redness and irritation at bay.

Can I use this moisturizing treatment with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying the treatment after your retinol to help calm and hydrate your skin. This type of routine for sensitive skin needs a product with soothing ingredients like glycerin and allantoin to keep skin comfortable and reduce irritation.

How often should I use this moisturizing treatment?

You can use this moisturizing treatment in the evening as part of your routine. Daily application helps improve skin moisture and is unlikely to irritate sensitive skin.

Health Science Reports, 2021Dermatology, 2003

Can this moisturizing treatment clog pores, cause breakouts or purging for sensitive skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for your sensitive skin because it avoids heavy ingredients, though sensitive skin still needs lightweight hydrators like hyaluronic acid and soothing agents like allantoin to stay calm and soft.

Can I use this moisturizing treatment around the eyes or on my body?

This moisturizing treatment can be used around the eyes and on the body, though the skin there is much thinner and may respond differently than facial skin. It is generally safe for sensitive skin because it avoids harsh ingredients and includes soothing agents like glycerin and allantoin.

Surgical and Radiologic Anatomy, 2002

Is this moisturizing treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.

    Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

  • Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

    Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

Ingredients

Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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