Peter Thomas Roth PEPTIDE SKINJECTION for dry sensitive skin
Glycerin
Tetrapeptide-1
Hyaluronic Acid
Average
- HighDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry sensitive skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration for your dry and sensitive skin, as glycerin and hyaluronic acid provide humectant benefits to plump and smooth the skin. Squalane further supports skin barrier function by offering emollient properties.
- The inclusion of allantoin and trehalose offers additional soothing and moisture-retention benefits, which are beneficial for dry or flaky skin concerns.
- The product is safe for your skin, containing no harsh ingredients and featuring soothing components like glycerin and hyaluronic acid.
How to apply
- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
People Say
★4.6Overall rating based on 200+ reviewsThis product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.
Highlights
Reduces fine lines Mostly Mentioned
- “Big change in forehead lines”
- “lines around eyes decreased”
- “definite reduction in lines”
Smooths skin texture Often Mentioned
- “Skin has never felt so smooth”
- “makeup goes on smooth”
- “melts into my skin”
Hydrating formula Sometimes Noted
- “Thick hydrating feel”
- “skin feels more hydrated”
- “helps hydrate”
Reduces eye puffiness Sometimes Noted
- “Less puffiness under eyes”
- “quick relief of puffiness”
- “noticed less puffiness”
Gritty serum texture Sometimes Noted
- “Lotion has a little grit”
- “texture is a little gritty”
- “creamy and a bit gritty”
High price point Sometimes Noted
- “hefty price”
- “less hefty price”
Drying sensation Rarely Noted
- “A bit drying”
- “skin did not feel oily”
Slow/No results Rarely Noted
- “Not noticed any reduction”
- “only been 12 days”
- “didn't last a week”
Sources: lovi.care, peterthomasroth.com, lovelyskin.com, dermstore.com, reddit.com, and more
Questions and answers
How well does Peptide Skinjection work for dry sensitive skin?
Peter Thomas Roth Peptide Skinjection works moderately well for dry sensitive skin, offering basic hydration and soothing benefits to help smooth and calm flaky areas. However, this skin type needs products with richer blends of deeply nourishing moisturizers, multiple forms of hyaluronic acid, and barrier-supporting ingredients to deliver lasting hydration and prevent dryness effectively.
Skin Research and Technology, 2024Clinical, Cosmetic and Investigational Dermatology, 2017
Which ingredients make this cream a good fit for dry sensitive skin?
Glycerin, hyaluronic acid, squalane, allantoin, and trehalose help plump, smooth, and calm dry sensitive skin while supporting the skin barrier. Products of this type need a blend of effective hydrating and soothing ingredients, multiple forms of hyaluronic acid, and pro vitamin B5 to deliver intense hydration and nourishment without any risk of irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017Skin Research and Technology, 2024
What does Glycerin do for dry sensitive skin?
Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008
What does Tetrapeptide-1 do for dry sensitive skin?
Tetrapeptide-1 helps improve skin firmness and supports the skin barrier for dry, sensitive skin. It may also help increase skin thickness and smooth out fine lines without causing irritation.
International Journal of Cosmetic Science, 2013Polymers, 2025
Where does this cream go in a skincare routine for dry sensitive skin?
This moisturizing treatment goes in the evening routine after your toner and before your moisturizer. A complete routine with a gentle cleanser and moisturizer helps improve dry skin.
The Journal of Dermatological Treatment, 2022Clinical, Cosmetic and Investigational Dermatology, 2017
Can I use this cream with retinol, and in what order?
You can use this treatment with retinol by applying it before your retinol at night to help keep your skin comfortable and smooth. Using a moisturizer or treatment that strengthens the skin barrier is unlikely to cause irritation and may help your skin tolerate retinol better.
How often should I use this cream?
This moisturizing treatment works well as an evening step in your routine for dry sensitive skin, helping to keep your face soft and comfortable. Daily application of moisturizers is unlikely to irritate your skin and helps improve hydration and barrier function over time.
Can this cream clog pores, cause breakouts or purging for dry sensitive skin?
This moisturizing treatment is unlikely to clog pores or cause breakouts for dry sensitive skin, as it contains no harsh ingredients and features soothing components like glycerin and hyaluronic acid. It is generally safe for your skin, though a product of this type needs richer, deeply nourishing ingredients and heavy barrier-protecting oils to fit dry sensitive skin even better.
Can I use this cream around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, as its gentle formula is well tolerated by sensitive skin. To truly comfort dry sensitive skin, a product of this type needs rich moisturizing ingredients and oils that lock in deep hydration and deeply soften flaky areas.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.
Skin Research and Technology, 2024The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Ingredients
Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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