NATURIUM Retinaldehyde Cream Serum 0.05% for sensitive skin
Retinaldehyde
Biofermented Oligopeptide- Retinal
Amino Acids
Punica Granatum Seed Extract
Average
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for sensitive skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate exfoliation and hydration for your normal skin, with retinaldehyde effectively minimizing fine lines and Glycerin providing humectant action.
- While Tocopherol and yeast extract offer general skincare benefits supportive for redness and irritation, they are not specifically targeted to address these concerns.
- The formulation is safe for your normal skin with sensitivity, as it lacks prohibited or harsh ingredients and poses no risk of irritation.
How to apply
- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
People Say
★4.6Overall rating based on 400+ reviewsThis serum is widely praised as an excellent, gentle introduction to retinaldehyde, with users reporting visible improvements in skin texture, brightness, and acne control without the harsh irritation often associated with retinoids.
Highlights
Gentle & Non-irritating Mostly Mentioned
- “zero irritation”
- “skin friendly”
- “gentle formula”
- “no sensitivity”
Improves Texture & Tone Often Mentioned
- “skin is glowing”
- “smoother texture”
- “even tone”
- “faded dark spots”
Pleasant Texture Often Mentioned
- “lightweight”
- “absorbs well”
- “creamy serum”
- “hydrating feel”
Effective for Acne Sometimes Noted
- “holygrail for acne”
- “reduction in breakouts”
- “unclogs pores”
- “fades post-acne marks”
Great Value Sometimes Noted
- “affordable price”
- “great price point”
- “well priced”
- “good value”
Slow results Sometimes Noted
- “taken weeks/months”
- “slow progress”
- “not huge difference”
- “needs time”
Breakouts/Purging Rarely Noted
- “tiny bumps appeared”
- “small pimples”
- “caused breakout”
- “purging phase”
Dryness Rarely Noted
- “makes skin dry”
- “caused flakiness”
- “not hydrating enough”
- “dried out patches”
Skin irritation Rarely Noted
- “burning and itching”
- “caused rashes”
- “redness after use”
Sources: lovi.care, naturium.com, target.com, spacenk.com, reddit.com, youtube.com, and more
Questions and answers
How well does Naturium Retinaldehyde Cream Serum 0.05% work for sensitive skin?
This product works for sensitive skin, though other treatments fit it better because it lacks ingredients specifically targeted to soothe redness and irritation. Sensitive skin needs treatments with ingredients like niacinamide, snail secretion filtrate, and antioxidants that actively calm redness while keeping the skin hydrated and healthy.
Which ingredients make this serum a good fit for sensitive skin?
Glycerin, tocopherol, and yeast extract make this serum a good fit for sensitive skin by providing hydration and supporting skin health, though treatments that rate higher for this skin need ingredients that specifically target redness and irritation.
What does Retinal do for sensitive skin?
Retinal helps smooth fine lines, improve texture, and even out skin tone while generally maintaining a good tolerance profile with a lower likelihood of irritation compared to stronger forms of vitamin A.
What does Biofermented Oligopeptide do for sensitive skin?
Biofermented Oligopeptide is unlikely to irritate sensitive skin and may help keep it calm. This ingredient supports a smooth, comfortable feel without causing unwanted redness or flare-ups.
Where does this serum go in a skincare routine for sensitive skin?
This serum goes in your evening routine after your cleansing and toning steps, followed by a moisturizer. A product for this skin needs soothing ingredients and calming hydrators that actively reduce redness and irritation.
Can I use this serum with glycolic acid, and in what order?
It is best to avoid using this serum and glycolic acid at the same time, as layering two strong exfoliants may easily dry and irritate sensitive skin. Instead, alternate the nights you use them or apply glycolic acid in the morning and reserve this treatment for your evening routine.
How often should I use this serum?
Use this serum in your evening routine once a week to start, and you may slowly use it more often if your skin tolerates it well. Retinaldehyde helps smooth fine lines while glycerin keeps skin hydrated, but sensitive skin needs extra soothing and calming ingredients to keep it comfortable.
Can this serum clog pores, cause breakouts or purging for sensitive skin?
Yes, this serum may cause breakouts or purging for sensitive skin, as reviewer complaints and the risk of irritation are low, but it includes active ingredients that speed up skin renewal. To better fit sensitive skin, a product of this type needs calming ingredients and soothing plant extracts that protect against redness while keeping pores clear.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors.
Journal of Clinical Medicine, 2023Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index.
Journal of Cosmetic Dermatology, 2018Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance.
Dermatology, 2002Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients.
Dermatology, 1999Phenolic-rich pomegranate peel extract formulated into a serum and mask showed significantly better facial skin lightening efficacy than placebo in 30 volunteers over 28 days.
Planta Medica, 2020Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo.
Clinical, Cosmetic and Investigational Dermatology, 2015A topical microemulsion containing Punica granatum extract significantly reduced skin erythema and melanin compared to a placebo in healthy Asian subjects over 12 weeks.
Postepy Dermatologii I Alergologii, 2014
Why other serums fit sensitive skin better
Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control.
European Journal of Pharmaceutics and Biopharmaceutics, 2016
Ingredients
Water, Glycerin, Propanediol, Triheptanoin, C13-15 Alkane, Coco-Caprylate Caprate, Carbomer, Yeast Extract, Apricot Polyglyceryl-6 Esters Kernel Oil, Amino Acids, Punica Granatum Seed Extract, Cetyl Diglyceryl Tris Trimethylsiloxy Silylethyl Dimethicone, Hydrolyzed Yeast Extract, Olivine Extract, Dilinoleic Acid Butanediol Copolymer, Cellulose, Phenoxyethanol, Sorbitan Oleate, Sodium Metabisulfite, Retinal, Guanosine, Uracil, Polyacrylate Crosspolymer-6, C9-12 Alkane, Caprylyl Glycol, Polyglyceryl-10 Dipalmitate, Dipropylene Glycol, Sodium Hydroxide, Glyceryl Polyacrylate, Tocopherol, Pvm Ma Copolymer, Adenosine Phosphate, Castor Ipdi Copolymer Oil, Potassium Sorbate, Hexadecene, Sodium Benzoate, T-Butyl Alcohol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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