Charlotte Tilbury Charlotte's Magic Serum Crystal Elixir for dry sensitive skin

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Poly-gamma-glutamic acid derived from a novel Bacillus subtilis strain dose-dependently increased skin barrier markers, hyaluronic acid synthesis, and aquaporin 3 expression in keratinocytes, and elevated filaggrin, involucrin, CD44, and aquaporin 3 expression in a reconstructed skin model compared to the control.

  International Journal of Molecular Sciences, 2025

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• Topically delivered gold-coated silica microparticles combined with laser pulses reduced inflammatory lesions compared with sham treatments in patients with moderate-to-severe facial acne.

  The Journal of Investigative Dermatology, 2015

• Laser-activated gold microparticles combined with topical retinoids reduced inflammatory lesion counts by 68% at month 12 in 52 patients with mild-to-moderate inflammatory facial acne.

  Journal of Drugs in Dermatology, 2023

• Combined treatment with a micro-diamond and micro-gold topical serum and a 1064 nm picosecond Nd:YAG laser produced moderate clinical improvement and high participant satisfaction in 40% of participants for facial skin rejuvenation with minimal side effects.

  Dermatologic Therapy, 2022

Why other moisturizers fit dry sensitive skin better

• Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

  Arzneimittel-Forschung, 2000

• Applying a lotion containing probiotic ferment lysate VHProbi® Mix R for 30 days significantly decreased transepidermal water loss and skin redness while significantly increasing skin moisturization compared to baseline in participants with sensitive skin.

  Scientific Reports, 2023

• Aged Punica granatum extract significantly reduced UV-induced erythema and melanin levels while improving skin hydration and lightness compared to placebo in 60 women.

  Food Science & Nutrition, 2025

Ingredients

Water, Niacinamide, Glycereth-26, Triheptanoin, Glycerin, Methyl Gluceth-20, Silica, Camellia Oleifera Seed Oil, Quartz Powder, Amethyst Powder, Ruby Powder, Gold, Butyrospermum Parkii Oil Shea Oil, Phenoxyethanol, Dimethyl Isosorbide, Polysorbate 20, Glyceryl Stearate, Butylene Glycol, Octyldodecyl Oleate, Benzyl Alcohol, Myrothamnus Flabellifolia Leaf Extract, Peg-100 Stearate, Octyldodecyl Stearoyl Stearate, Schisandra Chinensis Fruit Extract Magnolia Grandiflora Fruit Extract, Carbomer, Sodium Gluconate, Sodium Hyaluronate, Chondrus Crispus Extract, Sodium Hydroxide, Saussurea Involucrata Callus Extract, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice, Polyglutamic Acid, Pentylene Glycol, Sorbitol, Magnesium Aspartate, Zinc Gluconate, Rosa Canina Fruit Extract, Polyhydroxystearic Acid, Octyldodecanol, Sodium Benzoate, Propanediol, Biosaccharide Gum-4, Xanthan Gum, Parfum, Plumeria Alba Flower Extract, Plumeria Rubra Flower Extract, Lithothamnion Calcareum Extract, Lactic Acid, Potassium Sorbate, Caprylyl Glycol, Copper Gluconate, Hydrated Silica, 1,2-Hexanediol, Citric Acid, Solanum Tuberosum Extract Pulp, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Dehydroacetic Acid, Ascorbic Acid, Glutathione, Limonene, Geraniol, Citronellol, Linalool, Citral

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.