Charlotte Tilbury vs REN Clean Skincare

Questions and answers

Research behind their key ingredients

• Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin

  Retinol · The Journal of Investigative Dermatology, 2000

• Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

  Sodium hyaluronate · Dermatologic Therapy, 2022

• Improvement of naturally aged skin with vitamin A (retinol)

  Retinol · Archives of Dermatology, 2007

• Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial

  Ascorbic acid · Journal of Cosmetic Dermatology, 2020

• Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo

  Retinol · International Journal of Cosmetic Science, 2017

• Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing

  Retinol · The British Journal of Dermatology, 2019

• Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin

  Squalane · Scientific Reports, 2020

• Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation

  Ascorbic acid · Journal of Cosmetic Dermatology, 2020

• The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study

  Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017

• Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris

  Triethyl citrate · The British Journal of Dermatology, 2007

• Polyglycerol Ester-Based Low Energy Nanoemulsions with Red Raspberry Seed Oil and Fruit Extracts: Formulation Development toward Effective In Vitro/In Vivo Bioperformance

  Raspberry seed oil · Nanomaterials, 2021

• Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications

  Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015

• Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil

  Avocado oil · Journal of Cosmetic Dermatology, 2020

• Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin

  Superoxide dismutase · European Journal of Pharmaceutics and Biopharmaceutics, 2016

• Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release

  Oenothera biennis oil · Biomaterials Advances, 2022

• Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison

  Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2019

• Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract

  Salix nigra bark extract willow bark extract · Planta Medica, 2019

• An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging

  Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2010

• Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast

  Squalane · Molecules, 2025

• Melanogenesis effects of rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys on UVB-induced human epidermal melanocyte cells

  Hydrolyzed rice protein · Food & Function, 2020

• Influence of vitamin E acetate on stratum corneum hydration

  Tocopheryl acetate · Arzneimittel-Forschung, 1998

• Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy

  Tocopheryl acetate · Scientific Reports, 2025

• Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin

  Camellia oleifera seed oil · International Journal of Cosmetic Science, 2026

• Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial

  Shea butter, African shea butter · Lasers in Medical Science, 2025

• Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism

  Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

• A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study

  Saccharide isomerate · The Journal of Dermatological Treatment, 2025

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.