Acwell 5.5 Licorice pH Balancing Cleansing Toner for mature skin

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Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Treatment with a rose extract activated newly identified skin olfactory receptors and prevented epinephrine-induced skin stress responses in epidermal keratinocytes and human skin explants, while clinically decreasing the appearance of under-eye dark circles in stressed women.

  Molecules, 2020

• Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.

  Experimental Dermatology, 2015

• Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.

  Evidence-based Complementary and Alternative Medicine, 2015

• Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.

  Advanced Science, 2025

• Topical application of Glycyrrhiza glabra and Sophora japonica flavonoid-rich fractions individually and in combination significantly increased the wound healing rate and reduced oxidative stress compared to wound and Nolaver-treated groups.

  Molecules, 2023

• Topical application of the rhubarb charcoal-crosslinked chitosan/silk fibroin sponge scaffold effectively mitigated hepatic lipid accumulation, decreased inflammation, and attenuated oxidative stress in db/db mice via the AMPK signalling pathway.

  Lipids in Health and Disease, 2024

• Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.

  Journal of Clinical and Diagnostic Research, 2017

• Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.

  Experimental Dermatology, 2009

• An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.

  Clinical, Cosmetic and Investigational Dermatology, 2019

• A toner with 6% guava extract significantly reduced skin oiliness on the forehead and nose compared to the base toner in 21 volunteers over 28 days.

  Journal of Cosmetic Dermatology, 2019

• Pre-incubation with guava crude extract significantly decreased apoptotic and dead cells and markers of oxidative damage while improving antioxidant enzyme activity in human dermal fibroblasts subjected to AAPH-mediated oxidative stress, compared to cells subjected to stress without prior pre-incubation.

  Plant Foods for Human Nutrition, 2018

Ingredients

Water, Glycyrrhiza Glabra Root Licorice Root Water Root, Peg-6 Caprylic Capric Glycerides, Peg-7 Glyceryl Cocoate, Dipropylene Glycol, 1,2-Hexanediol, Poloxamer 184, Phenoxyethanol, Glycerin, Butylene Glycol, Rheum Palmatum Root Extract, Psidium Guajava Leaf Extract, Rosa Centifolia Flower Extract, Camellia Sinensis Leaf Extract, Perilla Ocymoides Seed Extract, Poncirus Trifoliata Fruit Extract, Bergamot Oil Fruit, Sodium Citrate, Disodium Edta, Citric Acid, Tocopheryl Acetate, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Paeonia Albiflora Root Extract, Cimicifuga Dahurica Root Extract, Pueraria Lobata Root Extract, Propylene Glycol, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.