Vitamin C and copper
Keep them apart
Apply vitamin C in the morning and copper peptides at night, because combining them directly makes both ingredients less effective on skin. Copper can break down vitamin C and make it less potent, meaning a shopper might not get the full glow and anti-aging benefits. The shopper can easily fix this by using one in the morning and the other at night, or by waiting longer between applying them.
Microneedle-Mediated Delivery of Copper Peptide Through Skin
Vitamin C products
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Olay
Super Serum
CA$18.98
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Charlotte Tilbury
Charlotte's Magic Cream
CA$43.50
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RoC
Retinol Correxion Deep Wrinkle Night Cream
CA$42.99
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Paula's Choice
1% Retinol Treatment
CA$70.50
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Summer Fridays
Jet Lag Mask
CA$66.00
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Mad Hippie
Vitamin C Serum
CA$42.99
- Eve Lom Renewal Treatment Oil
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ZO Skin Health
Exfoliating Polish
CA$92.80
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CeraVe
Skin Renewing Vitamin C Serum
CA$33.14
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Eucerin
Anti-Pigment Dual Serum
CA$66.59
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RoC
Retinol Correxion Deep Wrinkle Serum
CA$47.99
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iS Clinical
Cleansing Complex
CA$82.99
Copper products
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Minimalist
Vitamin B5 10% Moisturizer
CA$11.99
Questions and answers
Can you use vitamin C and copper together?
Which goes first, vitamin C or copper?
Keep vitamin C and copper apart by using them in separate routines because copper acts as an oxidation catalyst that reduces peptide efficacy and oxidizes ascorbate.
Are vitamin C and copper good for sensitive skin?
You should keep vitamin C and copper apart because copper oxidizes vitamin C and reduces peptide efficacy. It is best to use them in separate routines to avoid irritation.
Research on vitamin C and copper
Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Efficacy of ethyl ascorbyl ether-containing cosmetic cream on blue light-induced skin changes
Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations
Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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