Eighth Day skincare

Questions and answers

Research behind Eighth Day's key ingredients

• Hyaluronic acid and wound healing

  Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015

• The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer

  Niacinamide · The British Journal of Dermatology, 2002

• Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation

  Niacinamide · Antioxidants, 2021

• Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

  Sodium hyaluronate · Dermatologic Therapy, 2022

• The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction

  Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

• Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy

  Niacinamide · Journal of Cosmetic Dermatology, 2021

• The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study

  Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017

• The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study

  Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013

• Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging

  Niacinamide · Scientific Reports, 2024

• Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial

  Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin

  Acetyl hexapeptide-8 · Annals of Dermatology, 2019

• Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids

  Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002

• Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects

  Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025

• The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects

  Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013

• Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study

  Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026

• Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee Venom-Derived Face Serum on Skin Health and Signs of Aging

  Manuka honey · Cureus, 2025

Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.