Skinfix Barrier+ Triple Lipid-Peptide Face Cream for mature skin

How to apply

Questions and answers

What the research says

• Application of Body Lotion for 5 weeks on cosmetic dry skin improved barrier properties, increased levels of cholesterol, ceramides, and long-chain fatty acids, increased beneficial skin bacteria, and enhanced microbiome functional potential compared to baseline.

  Scientific Reports, 2022

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.

  Skin Pharmacology and Physiology, 2022

• Topical application of a pseudo-ceramide-containing spray improved stratum corneum water content, transepidermal water loss, cell area, and scaling score, and normalized the ceramide profile in patients with dry and sensitive skin compared to a control spray.

  Journal of Cosmetic Dermatology, 2025

• Topical calcineurin inhibitors delay barrier recovery, decrease epidermal lipid synthesis and lamellar body secretion, and suppress antimicrobial peptides in normal humans and hairless mice, while co-application of physiologic lipid mixture normalizes these abnormalities.

  Experimental Dermatology, 2010

• Daily application of physiological lipid mixture containing emulsion protects healthy skin and promotes repair on impaired barrier skin, reducing TEWL and maintaining stratum corneum hydration in nine healthy Caucasian volunteers.

  Giornale Italiano Di Dermatologia E Venereologia, 2014

• Topical application of a cholesterol-dominant 3:1:1:1 lipid mixture accelerated barrier recovery compared to vehicle and equimolar mixtures in chronologically aged murine and human skin.

  Journal of the American Academy of Dermatology, 1997

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

Ingredients

Water, Caprylic Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter Shea Butter, Olus Oil, Cetyl Lactate, C12-16 Alcohols, Caprylyl Caprylate Caprate, Propanediol, Jojoba Macadamia Esters Seed Oil Oil, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Ceramide Np, Ceramide Ap, Ceramide Eop, Rice Bran Extract, Dilinoleic Acid Propanediol Copolymer, Squalane, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract Soybean Extract, Pentylene Glycol, Potassium Sorbate, Hydrolyzed Rice Protein, Chondrus Crispus Extract, Hydrogenated Glycerides, Helianthus Annuus Seed Oil Sunflower Seed Oil, Ethylhexylglycerin, Citric Acid, Phytosteryl Macadamiate, Aloe Barbadensis Leaf Juice, Trisodium Ethylenediamine Disuccinate, Tocopherol, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Phytosterols, Sodium Lauroyl Lactylate, Gluconolactone, Phenethyl Alcohol, Sodium Benzoate, Sodium Hyaluronate, Cholesterol, Carbomer

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.