RoC Retinol Correxion Deep Wrinkle Daily Moisturizer for oily skin

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Questions and answers

What the research says

• Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.

  International Journal of Cosmetic Science, 2017

• A combination of dermapen and glycolic acid peel significantly decreased acne scar grades and resulted in higher patient satisfaction compared to either monotherapy in 30 patients.

  Journal of Cosmetic Dermatology, 2019

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects.

  Journal of Drugs in Dermatology, 2025

• The application of a sunscreen formulation containing ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene does not significantly affect critical acne-related species such as Cutibacterium acnes and Staphylococcus epidermidis, refuting the induction of facial dysbiosis in men.

  Archives of Dermatological Research, 2024

• Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.

  The British Journal of Dermatology, 2019

• Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.

  Journal of Controlled Release, 2018

• Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.

  Archives of Dermatological Research, 2017

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent.

  Journal of Pharmaceutical and Biomedical Analysis, 2011

• Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2008

• Dermal application of a sunscreen containing 10% homosalate in four volunteers resulted in delayed elimination with terminal half-times around 24 h and a bioavailability of cis-homosalate a factor of 2 lower than trans-homosalate, while metabolite ratios supported using oral-route urinary excretion fractions for dermal exposure assessments.

  Archives of Toxicology, 2024

• Homosalate exhibited the highest permeation among tested filters with a relative permeability rate of 4.2% and a depth of 60 um, and specific thickeners and emulsifiers successfully reduced its permeation without inhibiting the skin permeation of niacinamide.

  Photodermatology, Photoimmunology & Photomedicine, 2026

• An online-SPE-LC-MS/MS method successfully quantified specific urinary homosalate metabolites for up to 96 hours after dermal sunscreen application in a volunteer and detected metabolites exclusively in three German pilot participants who had used sunscreen within five days.

  Analytica Chimica Acta, 2021

• Incorporating rosmarinic acid into sunscreens enhanced the in vivo SPF of octocrylene by over 157% and reduced lipid peroxidation in the human stratum corneum.

  Antioxidants, 2025

• Early application of sunscreen after ablative fractional skin resurfacing significantly increased the sensitization rate of the UV-filter, octocrylene, and the sunscreen compared to intact skin.

  The Journal of Dermatological Treatment, 2015

• Dermal sunscreen exposure in 20 healthy volunteers led to plasma concentrations of avobenzone, octocrylene, and its metabolite CDAA reaching up to 11 μg/L, 25 μg/L, and 1352 μg/L, respectively.

  Environment International, 2019

• Daily whole-body topical application of sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methylbenzylidene) camphor results in systemic absorption in healthy human volunteers but does not alter endogenous reproductive hormone levels.

  The Journal of Investigative Dermatology, 2004

• Topical application of sunscreen agents in human volunteers resulted in significant skin penetration of all agents and systemic absorption of oxybenzone and its metabolites.

  Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 2004

• Benzophenone-3 loaded starch microsponges provided improved photoprotection, higher sun protection factor, and reduced cutaneous penetration compared to raw benzophenone-3 cream.

  Materials Science & Engineering. C, Materials for Biological Applications, 2019

Ingredients

Avobenzone, Homosalate, Octocrylene, Oxybenzone, Water, Glycerin, Tetrahydroxypropyl Ethylenediamine, Dimethicone, Cyclohexasiloxane, Butylene Glycol, Butyrospermum Parkii Butter Shea Butter, Squalane, Ppg-2 Myristyl Ether Propionate, Pentaerythrityl Tetraethylhexanoate, Cetyl Alcohol, Glyceryl Stearate, Diethylhexyl 2,6-Naphthalate, Aluminum Octenylsuccinate Starch, Peg-75 Stearate, Polyacrylamide, Glycolic Acid, Phenoxyethanol, Pentylene Glycol, Ammonium Acryloyldimethyltaurate Vp Copolymer, C13-14 Isoparaffin, Ceteth-20, Steareth-20, Methylparaben, Tocopheryl Acetate, Propylparaben, Ethylparaben, Laureth-7, Bht, Disodium Edta, Cyclopentasiloxane, P-Anisic Acid, Allantoin, Polysorbate 20, Retinol, Ascorbic Acid, Hydroxyphenyl Propamidobenzoic Acid, Sodium Hydroxide

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.