Pyunkang Yul Mist Toner for mature skin

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation.

  International Journal of Biological Macromolecules, 2020

• Topical steroid withdrawal is driven by excess mitochondrial NAD+ metabolism that can be successfully targeted using complex I-inhibiting interventions such as metformin and berberine.

  The Journal of Investigative Dermatology, 2025

• Topical steroid withdrawal presents as a distinct dermatopathology characterized by burning, flushing, thermodysregulation, and elevated mitochondrial NAD+ oxidation, which can be improved by targeting complex I with metformin or berberine.

  MedRxiv, 2024

• A carboxymethyl cellulose-based hydrogel film loaded with berberine reduced keratinocyte hyperproliferation by 25% and controlled oxidative stress and inflammation markers in vitro.

  Carbohydrate Polymers, 2022

• Berberine dose-dependently inhibited basal and TPA-induced expression and activity of MMP-9, and suppressed TPA-induced IL-6 expression in normal human keratinocytes.

  Phytomedicine, 2008

• Coptis chinensis Franch downregulates the expression and protease activity of KLK5 and cathelicidin, inhibits LL-37 processing, reduces pro-inflammatory cytokines, suppresses TLR2 signaling, and inhibits LL-37-induced endothelial cell proliferation in human epidermal keratinocytes.

  Molecules, 2020

• Berberine decreases basal and UV-induced MMP-1 expression and increases as well as recovers UV-reduced type I procollagen expression in human dermal fibroblasts.

  Phytomedicine, 2008

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

Ingredients

Coptis Japonica Extract, 1,2-Hexanediol, Butylene Glycol, Glycerin, Sodium Hyaluronate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.