🇦🇺Australia

Murad Retinal ReSculpt Overnight Treatment for dry skin

Average

  • AverageDry Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for dry skin; other serums fit it better.

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for your dry skin due to the humectant action of urea and trehalose, but it lacks sufficient emollient ingredients like shea butter in higher concentrations to fully address dryness.
  • The presence of retinal provides excellent wrinkle reduction by minimizing fine lines and wrinkles, though it may offer moderate exfoliation that is not ideal for your dry or flaky skin.
  • The product is safe for your dry skin, as it contains no harsh ingredients and includes soothing components like shea butter and oat kernel extract.

How to apply

  • Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
  • Place the serum after cleansing and toner, but right before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
  • Apply the serum on slightly damp skin to help lock in extra moisture.
  • Avoid the eye area and do a patch test before your first use.

People Say

★4.8Overall rating based on 600+ reviews

Users report this treatment effectively targets advanced signs of aging, leading to visibly firmer, smoother, and bouncier skin. It is frequently praised for delivering results on deep wrinkles and sagging without the typical irritation associated with potent retinoids.

Highlights

  • Visibly smooths texture Mostly Mentioned
    • “skin feels smooth and soft”
    • “noticeably smoother to the touch”
    • “improved texture after a few weeks”
  • Firms and lifts Often Mentioned
    • “jawline seems more defined”
    • “skin feels more taut”
    • “helps with sagging neck skin”
  • Gentle and non-irritating Often Mentioned
    • “no tingling or redness”
    • “great for sensitive skin”
    • “less irritating than prescription tretinoin”
  • High price point Often Mentioned
    • “too expensive for the amount”
    • “price tag is steep”
    • “hard to justify the cost”
  • Fast-acting results Sometimes Noted
    • “saw results in 2 weeks”
    • “immediate glow the next morning”
    • “works faster than retinol”
  • Pleasant consistency Sometimes Noted
    • “lightweight and absorbs easily”
    • “creamy but not greasy”
    • “soaks in quickly”
  • Deceiving packaging Sometimes Noted
    • “bottle looks big but holds little”
    • “bulky plastic packaging”
    • “hard to tell when empty”
  • Lack of results Rarely Noted
    • “no difference in 2 months”
    • “didn't do much for deep lines”
    • “expected more for the price”
  • Scent/Fragrance Rarely Noted
    • “has a floral scent”
    • “added fragrance not listed”
    • “smell is a bit strong”

Sources: lovi.care, ulta.com, murad.com, dermstore.com, lovelyskin.com, and more

Questions and answers

How well does Murad Retinal ReSculpt Overnight Treatment work for dry skin?

This treatment works okay for dry skin, offering some moisture with urea and trehalose, but it lacks enough rich, softening ingredients like shea butter to fully handle dryness. A treatment for dry skin needs more heavy-duty moisturizers, soothing barrier ingredients, and skin-repairing components like ceramides, peptides, and niacinamide.

Skin Research and Technology, 2024

Which ingredients make this treatment a good fit for dry skin?

This treatment works for dry skin thanks to urea and trehalose, which help hold on to moisture, along with soothing oat kernel extract and shea butter. A product of this type needs richer moisturizing ingredients and barrier-supporting additions like ceramides, niacinamide, or peptides to fully care for dry skin.

Journal of Drugs in Dermatology, 2015Journal of Drugs in Dermatology, 2016

What does Retinal do for dry skin?

Retinal helps smooth dry skin and is unlikely to cause severe dryness when used properly, though it may occasionally lead to mild scaling or irritation as the skin adjusts. This ingredient works best when paired with gentle moisturizers to keep the face feeling soft and comfortable.

Dermatology, 1999Clinical Interventions in Aging, 2006

What does Squalane do for dry skin?

Squalane helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture and prevents water loss. It is unlikely to cause irritation and may protect the skin from damage while improving overall hydration.

Advances in Food and Nutrition Research, 2012Molecules, 2009

Where does this treatment go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing. A product of this type works best for dry skin when it also includes rich softening and smoothing ingredients in higher amounts to fully comfort dryness.

Can I use this treatment with niacinamide, and in what order?

You can use this treatment with niacinamide by applying niacinamide first and following with this treatment once it absorbs. This approach helps keep your skin calm, though dry skin of this type needs more rich, softening ingredients and gentle hydration to fully address dryness.

Journal of Drugs in Dermatology, 2015Journal of Drugs in Dermatology, 2016

How often should I use this treatment?

You can use this treatment in your evening routine, starting just once a week to see how your skin reacts since it may cause flaking on dry skin. To properly care for dry skin, this type of product needs extra rich softening ingredients and heavy moisturizing butters to fully lock in hydration and prevent dryness.

Journal of Drugs in Dermatology, 2015Journal of Drugs in Dermatology, 2016

Can this treatment clog pores, cause breakouts or purging for dry skin?

This treatment is unlikely to clog pores or cause breakouts on dry skin, but the retinal it contains may cause mild flaking or purging as your skin adjusts. A product of this type needs richer softening ingredients and soothing extracts to fully comfort dry skin.

Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol and parfum). Cetearyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

What the research says

  • Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.

    Skin Research and Technology, 2024
  • Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline.

    Journal of Drugs in Dermatology, 2015
  • Colloidal oatmeal induced skin barrier-related gene expression in vitro and showed significant clinical improvements in skin dryness, moisturization, and barrier in 50 healthy female subjects treated with a colloidal oatmeal lotion.

    Journal of Drugs in Dermatology, 2016
  • A multiple W/O/W emulsion containing Rosmarinus officinalis L., Avena sativa L., and Linum usitatissimum L. extracts showed no irritant, phototoxic, inflammatory, or allergenic potential in human skin models and patch tests, establishing its safety as a cosmetic base.

    Pharmaceutics, 2021
  • Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index.

    Journal of Cosmetic Dermatology, 2018
  • Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance.

    Dermatology, 2002
  • Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients.

    Dermatology, 1999
  • Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

    Molecules, 2025
  • Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

    Antioxidants, 2025
  • A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

    Lasers in Medical Science, 2025
  • A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

    International Journal of Cosmetic Science, 2025
  • A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts.

    Clinical, Cosmetic and Investigational Dermatology, 2018
  • Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model.

    Skin Pharmacology and Applied Skin Physiology, 2002
  • Colloidal oat increased the growth rate, metabolism, and lactic acid production of Staphylococcus epidermidis compared to Staphylococcus aureus in vitro, matching clinical increases in lactic acid on dry skin after 6 weeks of lotion use.

    Clinical, Cosmetic and Investigational Dermatology, 2021
  • Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis.

    American Journal of Clinical Dermatology, 2002
  • Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues.

    Mycoses, 2012

Why other serums fit dry skin better

Ingredients

Water, Diisostearyl Malate, Pentylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Zea Mays Kernel Extract, Squalane, Propanediol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Glycerin, Cetearyl Alcohol, Glyceryl Ricinoleate, Avena Sativa Kernel Extract Oat Kernel Extract, Butyrospermum Parkii Butter Shea Butter, Retinal, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Anigozanthos Flavidus Extract, Phosphatidylcholine, Olea Europaea Leaf Extract Olive Leaf Extract, Mannitol, Ethylhexylglycerin, Dimethyl Isosorbide, Glyceryl Stearate, Sodium Stearoyl Glutamate, Cetyl Alcohol, Hectorite, Xanthan Gum, Sodium Chloride, Polysorbate 60, Sorbitan Isostearate, Leuconostoc Radish Root Ferment Filtrate, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Benzoate, Chlorphenesin, Potassium Sorbate, Citronellol, Alpha-Isomethyl Ionone, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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Prices checked 2 Nov 2026

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