Heliocare 360° Gel Oil-Free SPF 50+ for mature skin

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Questions and answers

What the research says

• Topical application or oral administration of Polypodium leucotomos extract inhibited ultraviolet-induced reactive oxygen species, lipid peroxidation, erythema, and skin photosensitization in guinea pig and human skin.

  Photodermatology, Photoimmunology & Photomedicine, 1996

• Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo.

  The Journal of Dermatological Treatment, 2025

• Topical application of micronised titanium dioxide results in no dermal absorption, with the particles being deposited solely on the outermost surface of the stratum corneum.

  Skin Pharmacology and Applied Skin Physiology, 2001

• Microfine titanium dioxide does not penetrate human skin when formulated in an oil-in-water emulsion with the pigment dispersed in the aqueous phase, compared to oily dispersions and liposomal encapsulation which allow deeper skin penetration.

  International Journal of Cosmetic Science, 2000

• Topical or oral administration of Polypodium leucotomos extract prevents acute sunburn, psoralen-induced phototoxic reactions, and depletion of Langerhans cells in healthy human volunteers by increasing the UV dose required for immediate pigment darkening, minimal erythema dose, and minimal phototoxic dose.

  Photodermatology, Photoimmunology & Photomedicine, 1997

• Polypodium leucotomos fern extract inhibits UV-induced reactive oxygen species production, DNA damage, apoptosis, necrosis, and matrix remodeling, translating to long-term prevention of photoaging and photocarcinogenesis.

  Photochemical & Photobiological Sciences, 2010

• Treatment with a combination of Polypodium leucotomos and Aspalathus linearis extracts preserves vitamin D receptor levels from oxidative stress-induced decline in HaCaT cell cultures and skin explants.

  Pharmaceuticals, 2026

• Poloxamer 407 nanoparticulate gels of caffeic acid slowed drug diffusion eight-fold compared to an aqueous solution and demonstrated an antioxidant protective effect on human skin explants exposed to cigarette smoke.

  Nanomaterials, 2020

• Microparticles containing caffeic acid produce a more homogeneous distribution in the stratum corneum and higher retention into hair follicles compared to free caffeic acid, enabling continuous drug release for folliculitis treatment.

  Saudi Pharmaceutical Journal, 2019

• Caffeic acid and ferulic acid inhibited UVA-induced cytotoxicity, oxidant formation, and MMP-1 activity and mRNA in human keratinocyte HaCaT cells while up-regulating antioxidant defense systems compared to irradiated cells without treatment.

  Photochemistry and Photobiology, 2012

• Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening.

  Dermatologic Therapy, 2022

• Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control.

  Journal of Cosmetic Dermatology, 2008

• Topical ferulic acid-containing formulations effectively reduce skin erythema, hyperpigmentation, and signs of aging in adults compared to baseline or alternative conditions.

  The Journal of Clinical and Aesthetic Dermatology, 2025

• Replacing microsized titanium dioxide and zinc oxide with nanoparticles in sunscreens eliminates opaqueness and alters UV protection balance while inducing (photo)cyto- and genotoxicity and penetrating viable skin layers during long-term exposures.

  Nanotechnology, Science and Applications, 2011

• Microfine zinc oxide and titanium dioxide do not penetrate the stratum corneum of porcine skin in vitro, indicating that their use in sunscreens does not pose a health risk from internal exposure.

  Toxicology in Vitro, 2006

• Hyaluronic acid-grafted titanium dioxide nanoparticles increased SPF from 13.3 to 19.1 while demonstrating low photocatalytic activity, exceptional thermal stability with >95% SPF retention, enhanced moisturization with >80% hydration retention, and minimal cytotoxicity with 88.5% cell viability in HaCaT keratinocytes compared to unmodified nanoparticles.

  International Journal of Biological Macromolecules, 2025

Ingredients

Water, C12-15 Alkyl Benzoate, Disodium Phenyl Dibenzimidazole Tetrasulfonate, Dicaprylyl Carbonate, C13-15 Alkane, C14-22 Alcohols, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Arginine, Hexylene Glycol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Dipropylene Glycol Dibenzoate, Butylene Glycol Cocoate, Phenylbenzimidazole Sulfonic Acid, Trilaureth-4 Phosphate, Ceteareth-25, C12-20 Alkyl Glucoside, Polypodium Leucotomos Leaf Extract, Ethylhexyl Ferulate, Ferulic Acid, Caffeic Acid, Physalis Angulata Extract, Ethylhexyl Triazone, Caprylyl Glycol, Melanin, Camellia Sinensis Extract, Arabidopsis Thaliana Extract, 3-O-Ethyl Ascorbic Acid, Oxothiazolidine, Phenylpropanol, Disodium Ethylene Dicocamide Peg-15 Disulfate, Diethylhexyl Butamido Triazone, Hydrolyzed Wheat Pvp Crosspolymer Protein, Ppg-15 Stearyl Ether Benzoate, Troxerutin, Glycerin, Silica, Propanediol, Stearalkonium Hectorite, Propylene Carbonate, Tocopheryl Acetate, Disodium Edta, Ethyl Lauroyl Arginate Hcl, Phytosphingosine Hcl, Caprylic Capric Triglyceride, Panthenyl Triacetate, Butylene Glycol, Ethyl Linoleate, Oleyl Alcohol, Lecithin, Sodium Benzoate, Tocopherol, Ci 77491, Ci 77492, Ci 77499, Parfum, Linalool, Limonene

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.