Dermol 500 Lotion for mature skin
Benzalkonium Chloride
Chlorhexidine Dihydrochloride
Liquid Paraffin
Isopropyl Myristate
Cetostearyl AlcoholCaution
- AverageNormal Skin Fit
- AverageEffectiveness
- ConcerningSafety
A poor match for mature skin; the moisturizers alongside fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for normal skin as liquid paraffin and isopropyl myristate provide emollient action, though the formula lacks sufficient humectants for optimal hydration.
- The product offers supportive benefits for wrinkles and fine lines due to the absence of specialized ingredients like retinoids or peptides that target collagen production.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.9Overall rating based on 1000+ reviewsIt is celebrated for its versatility as both a leave-on moisturizer and a soap substitute, providing rapid relief from itching and preventing secondary infections due to its antimicrobial properties.
Highlights
Versatile application Mostly Mentioned
- “Soap substitute”
- “shower gel”
- “leave-on moisturizer”
Excellent texture Often Mentioned
- “Non-greasy”
- “absorbs quickly”
- “light consistency”
Hand care Often Mentioned
- “Heals cracked hands”
- “non-drying wash”
- “gentle cleanser”
Rapid itch relief Often Mentioned
- “Soothes irritation”
- “stops scratching”
- “calms redness”
Antimicrobial benefits Sometimes Noted
- “Prevents infection”
- “clears folliculitis”
- “kills bacteria”
Adverse reactions Rarely Noted
- “Facial rash”
- “stinging sensation”
- “increased redness”
Insufficient for dryness Rarely Noted
- “Too thin”
- “not rich enough”
- “requires thicker cream”
Medicinal scent Rarely Noted
- “Weird smell”
- “chemical odor”
- “unpleasant scent”
Packaging issues Rarely Noted
- “Pump faults”
- “hard to empty”
- “broken dispenser”
Texture dislike Rarely Noted
- “Too runny”
- “watery consistency”
- “not lotion-like”
Sources: lovi.care, pharmica.co.uk, medino.com, chemist-4-u.com, amazon.com, chemistdirect.co.uk, and more
Questions and answers
Why does Lovi advise caution with Dermol 500 Lotion for mature skin?
Lovi advises caution because this lotion lacks specialized ingredients like retinoids or peptides that target collagen production for wrinkles and fine lines, and it does not have enough water-attracting ingredients for deep hydration. A moisturizing treatment for mature skin needs multiple hydrating agents and soothing extracts to maintain skin balance and target signs of aging.
Which ingredients make this lotion a poor fit for mature skin?
This lotion is a poor fit for mature skin because it lacks specialized ingredients like retinoids or peptides that target collagen production and smooth fine lines. A moisturizing treatment for mature skin needs active ingredients that boost collagen and richer hydrating agents to keep dry skin soft and plump.
What does Benzalkonium Chloride do for mature skin?
Benzalkonium chloride does not provide anti-aging benefits for mature skin and may cause irritation or compromise the skin barrier with repeated use. Mature skin needs nourishing ingredients like antioxidants, peptides, and rich moisturizers to improve firmness and keep it soft and smooth.
Regulatory Toxicology and Pharmacology, 2005Dermatosen in Beruf und Umwelt. Occupation and Environment, 1985
What does Chlorhexidine Dihydrochloride do for mature skin?
Chlorhexidine Dihydrochloride is an antiseptic agent that helps reduce bacteria on the skin, but it is not typically targeted for mature skin benefits. A product for mature skin needs nourishing ingredients and moisturizers that improve firmness, smooth fine lines, and keep dry skin soft.
Where does it go in a skincare routine for mature skin?
This moisturizing treatment goes in the moisturizer step of your morning and evening routines. Mature skin needs products with ingredients like retinoids or peptides to help with wrinkles and fine lines, which this formula lacks.
Can I use this lotion with retinol, and in what order?
You can use this lotion with retinol, applying the lotion first to help keep your skin comfortable and smooth. Using a moisturizer like this helps support your skin barrier while you use retinol, though mature skin also needs ingredients like retinoids or peptides to help with fine lines.
How often should I use it?
This lotion is a poor match for mature skin because it lacks key anti-aging ingredients and deep hydration. Mature skin needs products with powerful hydrators and specialized ingredients like retinoids or peptides to boost collagen and smooth fine lines.
Can this lotion clog pores, cause breakouts or purging for mature skin?
This lotion is unlikely to clog pores or cause breakouts for mature skin, though it may not provide enough rich moisture to keep dry mature skin feeling soft and smooth. A product of this type needs extra hydrators and firming ingredients like peptides or retinoids to properly care for mature skin.
Can I use it around the eyes or on my body?
This lotion is a poor match for mature skin because it lacks specialized ingredients like retinoids or peptides that target collagen production. To care for mature skin around the eyes or on the body, a product of this type needs added hydrating ingredients and components that support firmness.
Is this lotion fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Topical application of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and anti-inflammatory agents after ultrasound scalpel-assisted hemorrhoidectomy reduced pain and itching while accelerating complete wound healing at 4 weeks compared to washing with warm water alone in adult patients.
Annals of Coloproctology, 2024Topical therapy with 4% chlorhexidine digluconate products resolved clinical signs in all dogs with superficial pyoderma, including those with meticillin-resistant strains, showing comparable efficacy to systemic amoxicillin-clavulanic acid.
Veterinary Dermatology, 2015Repeated application of concentrated water-in-oil emulsions over four weeks caused no skin irritation, positively affected skin properties, and delivered almost 50% of the applied fluorescein sodium, with isopropyl myristate showing superior penetration performance compared to liquid paraffin in healthy volunteers.
International Journal of Pharmaceutics, 2019Increasing the softness of pressure-sensitive adhesives using isopropyl myristate decreased pain and stripped corneocytes during removal without significantly changing human skin dermal peeling force.
Skin Research and Technology, 2007A modern cold cream formulation using a self-emulsionable excipient with isopropyl myristate shows improved preparation ease, stability, rheological qualities, and moisture and emollient power compared to traditional cerates.
Bollettino Chimico Farmaceutico, 1996
Ingredients
Benzalkonium Chloride, Chlorhexidine Dihydrochloride, Liquid Paraffin, Isopropyl Myristate, Cetostearyl Alcohol, Cetomacrogol 1000, Phenoxyethanol, Water
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Elina Nazarenko, MD
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Victoria Derkova, MS
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