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Alastin Ultra Nourishing Moisturizer for mature skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Alastin Ultra Nourishing Moisturizer

Superior

  • HighNormal Skin Fit
  • HighEffectiveness
  • ExcellentSafety

One of the best moisturizers for mature skin.

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Excellent for your normal skin, this moisturizer effectively targets wrinkles and fine lines with Palmitoyl Tripeptide-1 and Palmitoyl Hexapeptide-12 to support collagen production and skin elasticity. Glycerin and Tremella Fuciformis Sporocarp Extract provide superior hydration and barrier support, aligning perfectly with your skin's needs.
  • The formula's rich blend of emollients like Caprylic Capric Triglyceride and humectants ensures deep moisturization and enhances barrier resilience for your normal skin.
  • Safety is well-addressed with soothing ingredients such as Bisabolol and Oat Kernel Extract, ensuring no irritation for your normal skin.

How to apply

  • Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
  • Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
  • Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
  • Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
  • Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.

People Say

★4.6Overall rating based on 200+ reviews

This moisturizer is highly rated for providing deep, lasting hydration without a heavy feel, making it suitable for dry, sensitive, and aging skin. It is frequently praised for improving skin texture, calming redness, and supporting the skin barrier, and is often used as a makeup base or for post-procedure care. The product is considered expensive by many users, and its availability is sometimes limited.

Highlights

  • Deeply hydrating Mostly Mentioned
    • “Only moisturizer that actually moisturizes”
    • “Amazingly hydrated”
    • “Delivers deep, lasting moisture”
  • Lightweight feel Often Mentioned
    • “Feels weightless and soft”
    • “Not heavy or greasy”
    • “Sinks in quickly”
  • Sensitive skin friendly Often Mentioned
    • “Perfect for my sensitive skin”
    • “Doesn't cause breakouts”
    • “Calms and comforts”
  • Expensive product Often Mentioned
    • “It's pricey but worth it”
    • “A little expensive”
    • “Cost is a factor”
  • Improves texture Sometimes Noted
    • “Skin is bright and soft”
    • “Helps the lines”
    • “Skin glows and looks plumper”
  • Limited availability Rarely Noted
    • “Only available through professionals”
    • “Hard to find in stores”

Sources: lovi.care, lovelyskin.com, realself.com, youtube.com, bestderm.com, ellemesmedspa.com, and more

Questions and answers

What makes Alastin Ultra Nourishing Moisturizer one of the best fits for mature skin?

This moisturizer is an exceptional fit because Palmitoyl Tripeptide-1 and Palmitoyl Hexapeptide-12 target wrinkles and fine lines to support collagen production and firmness. Glycerin and Tremella Fuciformis Sporocarp Extract provide deep hydration and barrier support, while Bisabolol and oat kernel extract keep skin calm and comfortable.

Journal of Cosmetic Dermatology, 2026Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for mature skin?

Palmitoyl Tripeptide-1 and Palmitoyl Hexapeptide-12 make this cream a great fit because they support collagen production to help smooth out wrinkles and firm up mature skin. Glycerin and Tremella Fuciformis Sporocarp Extract add deep hydration, while soothing ingredients like Bisabolol and Oat Kernel Extract help keep the skin calm and comfortable.

Journal of Cosmetic Dermatology, 2026ACS Applied Bio Materials, 2025

What does Trihex Technology do for mature skin?

Trihex Technology helps clear out damaged collagen and elastin in mature skin while supporting the production of fresh, healthy fibers to restore firmness and smooth the look of lines. Because it helps rebuild the underlying support network, this type of formula typically needs to include peptides and antioxidants to properly target the structural breakdown seen in aging skin.

Skin Pharmacology and Physiology, 2014Journal of Drugs in Dermatology, 2019

What does Palmitoyl Tripeptide-1 do for mature skin?

Palmitoyl tripeptide-1 helps improve firmness, smooths out wrinkles, and enhances skin brightness when used as part of an anti-aging routine. Studies show that when applied at night or combined with complementary peptides, it supports collagen production to make mature skin look more firm and elastic.

Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026

Where does this cream go in a skincare routine for mature skin?

This moisturizer goes near the end of your morning routine before sunscreen, and as the final step in your evening routine. Using it daily helps deeply hydrate mature skin, smooth fine lines, and support firmness.

The Journal of Dermatological Treatment, 2022Journal of Cosmetic Dermatology, 2026

Can I use it with retinol, and in what order?

You can use this moisturizer with retinol to help keep your skin comfortable and smooth. Apply your retinol treatment first, let it sink in, and then smooth on the moisturizer to lock in hydration.

Cutis, 2006

How often should I use this cream?

This cream fits mature skin very well and is gentle enough to use twice a day as part of your morning and evening routine. Regular daily use helps smooth fine lines, supports collagen production, and keeps dry skin deeply moisturized.

Journal of Cosmetic Dermatology, 2020Journal of Drugs in Dermatology, 2015

Can it clog pores, cause breakouts or purging for mature skin?

This moisturizer is unlikely to clog pores or cause breakouts for mature skin, as its soothing ingredients like bisabolol and oat kernel extract help prevent irritation. It also does not contain active exfoliating ingredients, so it will not cause purging.

Can I use it around the eyes or on my body?

This moisturizer is safe and effective to use on the thin skin around the eyes and on the body to smooth wrinkles and provide deep hydration. Its gentle ingredients and rich blend of moisturizers are well-suited to care for delicate areas without causing irritation.

Surgical and Radiologic Anatomy, 2002European Journal of Pharmaceutics and Biopharmaceutics, 2014

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

  • Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

    Journal of Cosmetic Dermatology, 2026

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Palmitoyl hexapeptide-12 permeates the stratum corneum and epidermis, initiating gel formation via endogenous ions and strengthening and repairing the skin barrier after delipidation in human skin.

    ACS Applied Bio Materials, 2025

  • Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization.

    Life, 2023

  • Pre-conditioning with TriHex Technology Serum Nectar 2.0 improved healing, global skin health, and extracellular matrix remodeling compared to a vehicle in 5 patients undergoing elective facelift surgery.

    Journal of Cosmetic Dermatology, 2025

  • Topical ReFORM & RePAIR COMPLEX with TriHex Technology significantly accelerated the resolution of internal fibrous banding and improved external scar quality compared with comparators in patients undergoing body contouring procedures.

    Aesthetic Surgery Journal. Open Forum, 2026

  • Topical application of TransFORM Body Treatment significantly increased adipose volume loss compared to placebo in 15 subjects following abdominal cryolipolysis or radiofrequency procedures over 12 weeks.

    Journal of Cosmetic Dermatology, 2020

  • A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

    Journal of Cosmetic Dermatology, 2015

  • Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

    International Journal of Cosmetic Science, 2026

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers.

    Journal of Cosmetic Dermatology, 2021

  • Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models.

    Archives of Dermatological Research, 2023

  • Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts.

    In Vivo, 2022

Ingredients

Water, Caprylic Capric Triglyceride, Caprylyl Methicone, Glycerin, Cetearyl Alcohol, Dimethicone, Glyceryl Oleate Citrate, Glyceryl Stearate, Potassium Cocoyl Hydrolyzed Oat Protein, Palmitoyl Tripeptide-1, Palmitoyl Hexapeptide-12, Helianthus Annuus Extract Sunflower Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Tremella Fuciformis Sporocarp Extract, Rice Bran Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Betaine, Bisabolol, Linoleic Acid, Tocopherol, Glyceryl Oleate, Caprylyl Glycol, Glycine Soja Soybean Sterols, Disodium Edta, Polyacrylate-13, Polyisobutene, Polysorbate 20, Caprylhydroxamic Acid, Ethylhexylglycerin, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play