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Peptide-rich plasma and protease

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Peptide-rich plasma and protease: keep them apart

Keep them apart

Use them at different times of day, applying the peptide serum in the morning and the protease product at night, because they cancel each other out. The protease breaks down the peptides so they cannot firm or smooth your skin. You can easily fix this by using one in the morning and the other at night.

Peptide-rich plasma products

Protease products

Questions and answers

Can you use peptide-rich plasma and protease together?

No, you should keep peptide-rich plasma and protease apart in your routine because the protease degrades the peptide bonds and renders the active ingredients inactive.

Which goes first, peptide-rich plasma or protease?

Keep peptide-rich plasma and protease apart in your routine because mixing them degrades peptide bonds and renders the actives inactive. You should use them in separate routines to avoid this interaction.

Are peptide-rich plasma and protease good for sensitive skin?

No, you should keep peptide-rich plasma and protease apart in your skincare routine. Proteases degrade peptide bonds and can render your peptide actives inactive.

Research on peptide-rich plasma and protease

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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