Galderma vs Deconstruct

Questions and answers

Research behind their key ingredients

• Topical benzoyl peroxide for acne

  Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020

• Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison

  Adapalene · American Journal of Clinical Dermatology, 2018

• Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure

  Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021

• The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study

  Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017

• Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug

  Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022

• A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial

  Adapalene · Archives of Dermatological Research, 2022

• Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15

  Silicon dioxide · Antioxidants, 2020

• Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection

  Silicon dioxide · Heliyon, 2020

• Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials

  Adapalene · Journal of the American Academy of Dermatology, 2023

• Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies

  Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023

• Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation

  Carbomer 940 · Gels, 2023

• In vivo and in vitro evaluation of octyl methoxycinnamate liposomes

  Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013

• Comparison of methods for assessing photoprotection against ultraviolet A in vivo

  Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987

• Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin

  Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025

• Facial disbiosis and UV filters

  Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.