SkinCeuticals Retinol 1.0 Maximum Strength Refining Night Cream for dry sensitive skin
Retinol
Glycerin
Butyrospermum Parkii Butter Shea Butter
Silybum Marianum Milk Extract
Passiflora Incarnata ExtractAverage
- AverageDry Skin Fit
- AverageEffectiveness
- Low RiskSafety
Works for dry sensitive skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for dry or flaky skin as retinol promotes smoothing texture and minimizing fine lines, though it may cause dryness and irritation for your sensitive skin. Bisabolol offers some soothing properties to counteract potential irritation.
- The formulation provides moderate skin refinement due to retinol's smoothing effects, but the high concentration may lead to dryness and irritation, making it moderately unsuitable for your dry and sensitive skin type.
How to apply
- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
People Say
★4.6Overall rating based on 2.3k+ reviewsBased on a very large amount of data, users consistently describe this cream as a powerhouse professional-grade treatment that delivers dramatic improvements in skin texture, clarity, and firmness, often outperforming prescription alternatives. While the results are highly praised, the majority of reviews emphasize that the retinization period—characterized by peeling, redness, and dryness—is intense and requires a slow, careful introduction to the routine.
Highlights
Effective anti-aging Mostly Mentioned
- “Lines around mouth vanished”
- “Forehead wrinkles significantly reduced”
- “Skin looks years younger”
Refines skin texture Mostly Mentioned
- “Texture is completely gone”
- “Skin feels like porcelain”
- “Smoothest my face has ever been”
Clears acne & pores Often Mentioned
- “Stopped my hormonal breakouts”
- “Pores look invisible now”
- “Faded dark spots from old acne”
Intense irritation Often Mentioned
- “Face peeled like a snake”
- “Burned my sensitive skin”
- “Redness lasted for days”
Fast-acting results Sometimes Noted
- “Saw difference in one week”
- “Woke up glowing”
- “Works faster than other brands”
Drying formula Sometimes Noted
- “Sucked moisture out of skin”
- “Must use heavy cream after”
- “Too drying for winter”
High price point Sometimes Noted
- “Hard on the wallet”
- “Very expensive for the size”
- “Wish it was cheaper”
Packaging design flaws Rarely Noted
- “Metal tube split on the side”
- “Product oozed out of cap”
- “Packaging is frustrating”
Sources: lovi.care, skinceuticals.com, dermstore.com, lovelyskin.com, bluemercury.com, amazon.com, and more
Questions and answers
How well does SkinCeuticals Retinol 1.0 work for dry sensitive skin?
This treatment offers moderate smoothing for your dry skin, but the high retinol concentration may cause dryness and irritation for your sensitive skin. Treatments that fit this skin best need rich hydrating and nourishing ingredients that provide deep moisture and protect the skin barrier without any risk of irritation.
Which ingredients make this cream a good fit for dry sensitive skin?
Glycerin, shea butter, and bisabolol help soothe and soften dry skin to offset the strong effects of retinol. A treatment for this skin needs gentle hydrating and nourishing ingredients that provide excellent moisture and texture improvement without any risk of irritation.
What does Retinol do for dry sensitive skin?
Retinol is often too strong for dry sensitive skin because it may cause scaling and stinging, so a product of this type needs gentle soothing ingredients and extra moisture to keep the skin calm and smooth.
The British Journal of Dermatology, 2019Toxicology Letters, 2003
What does Glycerin do for dry sensitive skin?
Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008
Where does this cream go in a skincare routine for dry sensitive skin?
This treatment goes in the evening routine after your toner and before your moisturizer. Because this product of this type can cause dryness and irritation for your dry and sensitive skin, it needs extra soothing ingredients and rich hydrators to keep your skin calm and comfortable.
Can I use this cream with glycolic acid, and in what order?
Using this cream with glycolic acid is not recommended, as combining these strong active ingredients makes dryness and irritation much more likely on your sensitive skin. If you do use both, apply them on alternate nights rather than together, and always follow with a rich moisturizer.
How often should I use this cream?
This cream works for your skin as an evening treatment, but because of its strength it may cause dryness and irritation, so you should start using it once a week. This type of product needs soothing ingredients and extra moisture to keep dry and sensitive skin calm and smooth.
Can this cream clog pores, cause breakouts or purging for dry sensitive skin?
This cream is unlikely to clog pores or cause breakouts, but it may cause purging, dryness, and irritation for your dry sensitive skin. A product for this skin needs gentle smoothing ingredients and soothing agents to keep skin calm and comfortable.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.
Archives of Dermatological Research, 2017Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels.
The Journal of Investigative Dermatology, 1995A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.
International Journal of Cosmetic Science, 2025Silybum marianum flower extract increased human hair follicle dermal papilla cell proliferation and VEGF production while suppressing cellular senescence, and in a clinical study using hair shampoo, it significantly increased hair density and total hair count at 16 and 24 weeks compared with a placebo group.
Journal of Cosmetic Dermatology, 2024Topical 0.5% silymarin-loaded antioxidant serum applied twice daily significantly reduced clinical acne severity, lesion counts, and melanin pigmentation in 22 Korean acne patients over 4 weeks without associated adverse events.
Journal of Cosmetic Dermatology, 2023Topical silymarin cream 1.4% showed comparable results to salicylic acid 30% peels in reducing acne severity in 30 patients with mild to moderate acne vulgaris.
Journal of Cutaneous Medicine and Surgery, 2024Topical chrysin nanoemulgel improved percutaneous absorption and in vitro cytotoxicity on A375 and SK-MEL-2 cell lines compared to unformulated chrysin, demonstrating effective localized transcutaneous delivery.
Pharmaceutics, 2021Chrysin attenuated apoptosis, ROS production, COX-2 expression, and AQP-3 down-regulation induced by UVB and UVA in HaCaT keratinocytes, while showing efficient percutaneous absorption and no skin irritation in animal studies.
Journal of Agricultural and Food Chemistry, 2011Chrysin treatment reduced injury area and inflammation while increasing bFGF secretion, promoting the healing of amiodarone extravasation-induced skin injury in rats compared to control and 10% DMSO groups.
Microvascular Research, 2022
Why other serums fit dry sensitive skin better
- Retinol in this serum
Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019
Ingredients
Water, Cyclomethicone, Cyclopentasiloxane, Propylene Glycol, Polysorbate 20, Allyl Methacrylate Crosspolymer, Hydrogenated Lecithin, Caprylic Capric Triglyceride, Butyrospermum Parkii Butter Shea Butter, Dimethiconol, Dimethicone, Dimethicone Peg-7 Isostearate, Retinol, Laureth-23, Laureth-4, Sodium Polyacrylate, Dimethicone Crosspolymer, Glycerin, Polyacrylamide, C13-14 Isoparaffin, Bht, Bisabolol, Tetrasodium Edta, Passiflora Incarnata Flower Extract, Rosa Canina Leaf Extract, Silybum Marianum Fruit Extract, Hypericum Perforatum Extract, Chamomilla Recutita Leaf Extract Matricaria Leaf Extract, Citric Acid, Methylisothiazolinone
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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