Rodan + Fields Redefine Multi-Function Eye Cream for mature skin

Questions and answers

What the research says

• Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

  Journal of Cosmetic Dermatology, 2026

• A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

  Journal of Cosmetic Dermatology, 2015

• Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

  International Journal of Cosmetic Science, 2026

• Topical application of Ginkgo biloba cream for two weeks reduced wrinkles and improved skin shape, texture, and tautness in human volunteers compared to baseline.

  Drug Development and Industrial Pharmacy, 2023

• Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo.

  Clinical, Cosmetic and Investigational Dermatology, 2015

• A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks.

  International Journal of Cosmetic Science, 2011

• Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects.

  Frontiers in Physiology, 2019

• Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid.

  AAPS PharmSciTech, 2021

• A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris.

  Clinical, Cosmetic and Investigational Dermatology, 2015

• A cosmetic formulation combining green tea and Ginkgo biloba extracts synergistically improved skin elasticity and skin barrier function in 48 volunteers compared to individual extracts.

  Journal of Drugs in Dermatology, 2014

• Laricitrin 3-rutinoside isolated from Ginkgo biloba fruits inhibited TNF-alpha-stimulated ROS generation, suppressed MMP-1 secretion, protected against collagen degradation, and diminished pro-inflammatory cytokines IL-6 and IL-8 in normal human dermal fibroblasts.

  Antioxidants, 2023

• Honey-based dressings reduced mean healing duration, length of hospital stay, and VAS pain scores compared with povidone iodine-based dressings in 1236 participants.

  Journal of Wound Care, 2021

• Topical honey application improved the mean duration of attacks and pain, occurrence of crusting, and healing time compared to acyclovir cream in 16 adult patients with recurrent labial and genital herpes lesions.

  Medical Science Monitor, 2004

Ingredients

Water, Dimethicone, Ethylhexyl Palmitate, Caprylic Capric Myristic Stearic Triglyceride, Glyceryl Stearate, Peg-100 Stearate, Polysilicone-11, Butylene Glycol, Steareth-2, Glycerin, Macadamia Ternifolia Seed Oil, Cetyl Alcohol, Caffeine, Hydrogenated Polyisobutene, Silica, Phenoxyethanol, Saccharomyces Lysate Extract, Caprylyl Glycol, Chlorphenesin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Aminomethyl Propanol, Steareth-20, Polyurethane-40, Lecithin, Ginkgo Biloba Leaf Extract, Honey Extract, N-Hydroxysuccinimide, Tetrapeptide-21, Tetrapeptide-16, Tranexamic Acid, Chrysin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Mica, Titanium Dioxide Ci 77891

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.