NATURIUM Azelaic Topical Acid 10% for mature skin
Azelaic Acid
Niacinamide
Ethyl Ascorbic Acid Ascorbic Acid
Potassium Azeloyl Diglycinate
Sodium HyaluronateHigh
- HighNormal Skin Fit
- HighEffectiveness
- HighSafety
A great choice for mature skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your normal skin, this formula features potassium azeloyl diglycinate and niacinamide to help regulate sebum and repair your skin barrier, addressing your concerns about wrinkles and fine lines by promoting collagen production and antioxidant protection.
- Ethyl ascorbic acid further enhances skin tone evening and provides antioxidant benefits, complementing the primary ingredients.
- The product is safe for your skin, with no reported risks of irritation due to the absence of harsh or prohibited ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.4Overall rating based on 600+ reviewsMost users report improved skin texture and a brighter complexion without experiencing irritation. A smaller number of users noted initial breakouts or found the scent to be unpleasant.
Highlights
Improves texture Mostly Mentioned
- “face is so smooth”
- “visibly reduced dark spots”
- “brighter looking skin”
Clears acne Often Mentioned
- “decreased congestion”
- “nodules gone”
- “acne improving so much”
Gentle and non-irritating Often Mentioned
- “zero irritation”
- “comfortable and hydrated”
- “suitable for sensitive skin”
Reduces redness Often Mentioned
- “calms red, pain and cysts”
- “reduction in baseline redness”
Elegant texture Sometimes Noted
- “soaks in immediately”
- “leaves no residue”
- “layers well”
Unpleasant smell Sometimes Noted
- “smells like Elmer's glue”
- “smells like old spit”
- “awful smell”
Drying or sticky Rarely Noted
- “little drying”
- “leaves a very sticky feeling”
- “not moisturizing enough”
Initial breakouts Rarely Noted
- “broke me out”
- “purging window”
- “five/six spots at a time”
Slow results Rarely Noted
- “plateaued after a few weeks”
- “didn't completely clear skin”
- “too soon to tell”
Sources: lovi.care, naturium.com, target.com, ulta.com, thingtesting.com, skinsort.com, and more
Questions and answers
What makes Naturium Azelaic Topical Acid 10% a great fit for mature skin?
This formula is a great fit for mature skin because it uses niacinamide and potassium azeloyl diglycinate to help smooth wrinkles and fine lines by supporting collagen production and repairing your skin barrier. It also includes vitamin C derivatives to help even out your skin tone and provide antioxidant protection. The product is very safe for your skin, with no reported risks of irritation.
Which ingredients make this cream a good fit for mature skin?
This cream is a great fit for mature skin because it contains potassium azeloyl diglycinate and niacinamide to help repair your skin barrier and reduce wrinkles. Ethyl ascorbic acid and sodium hyaluronate further help smooth your skin and protect it against aging.
Journal of Cosmetic Dermatology, 2021Scientific Reports, 2024
What does Azelaic Acid do for mature skin?
Azelaic acid helps mature skin by targeting dark spots and uneven tone, while supporting smoother texture and a more youthful look. It provides antioxidant benefits that may reduce signs of aging and protect skin from environmental stress.
Frontiers in Medicine, 2026Journal of Cosmetic Dermatology, 2022
What does Niacinamide do for mature skin?
Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Where does this cream go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Treatments are placed in the evening for simplicity and extra safety around sun exposure.
Can I use this cream with retinol, and in what order?
You can use this treatment alongside retinol, but to keep your skin calm, apply retinol on alternate nights or use it in your morning routine while saving this product for the evening. This helps prevent irritation while still giving you the smoothing and barrier-repairing benefits of both ingredients.
Journal of Cosmetic Dermatology, 2021Scientific Reports, 2024
How often should I use this cream?
This treatment is a great fit to use in your evening routine once a week to start, and you can carefully use it more often if your skin tolerates it well and shows good results. It is unlikely to cause irritation because it leaves out harsh or prohibited ingredients.
Facial Plastic Surgery, 2014Journal of Cosmetic Dermatology, 2021
Can this cream clog pores, cause breakouts or purging for mature skin?
This cream has a low likelihood of causing initial breakouts for mature skin and is safe without harsh ingredients. It helps smooth lines while supporting your skin barrier.
Journal of Cosmetic Dermatology, 2021Scientific Reports, 2024
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.
Scientific Reports, 2024Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated.
Antioxidants, 2021Topical delivery of L-ascorbic acid derivatives via emulgels increased skin hydration and skin whitening potential without significantly altering TEWL or pH over a 30-day in vivo study.
Pharmaceutics, 2023Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne.
Pharmaceutics, 2021Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo.
Dermatology and Therapy, 2024Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks.
Journal of the European Academy of Dermatology and Venereology, 2023Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline.
Journal of Cosmetic and Laser Therapy, 2006Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Ingredients
Water, Propanediol, Potassium Azeloyl Diglycinate, Polyacrylate Crosspolymer-6, Niacinamide, Ethyl Ascorbic Acid, Caprylyl Glycol, Coffea Arabica Seed Extract Coffee Seed Extract, Sodium Hyaluronate, Phenylpropanol, Phenoxyethanol, Citric Acid, Potassium Chloride, Glycerin, Chlorphenesin, Tocopherol, Potassium Sorbate, Sodium Benzoate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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