MISSHA Time Revolution Night Repair Ampoule Cream 5X for oily acne-prone skin

Extreme Biome
Bifida Lysate Ferment
Niacinamide
Centella Asiatica Extract
Ceramide Np
Average
- AverageOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily acne-prone skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your oily skin as niacinamide helps regulate oil production, while bifida ferment lysate and glycerin provide essential hydration and support your skin barrier. This combination offers general skincare benefits that are supportive but not specifically targeted for your acne, blemishes, and breakouts.
- The formula is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
- It provides excellent moisturizing and barrier-enhancing treatment, though stronger ingredients specifically for acne treatment would further improve its effectiveness for your main concerns.
How to apply
- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
People Say
★4.6Overall rating based on 400+ reviewsThis anti-aging night cream is highly effective for dry and mature skin, providing deep hydration and plumping for a softer, glowing, and more elastic complexion. While many users appreciate its rich, nourishing texture and good value, some with oily or acne-prone skin find it too heavy and occasionally experience breakouts or a greasy finish.
Highlights
Deeply moisturizing Mostly Mentioned
- “deeply hydrates and smooths”
- “perfect for dry skin in winter”
- “woke up with plump skin”
- “skin feels velvety soft”
Improves texture Often Mentioned
- “restores elasticity”
- “skin looks younger”
- “refines skin texture”
- “makes face glowy”
Good value Sometimes Noted
- “great value for money”
- “better than expensive brands”
- “affordable anti-aging”
- “high quality ingredients”
Rich consistency Sometimes Noted
- “rich nourishing formula”
- “thick but spreads well”
- “feels luxurious”
- “comforting night cream”
Heavy or greasy Sometimes Noted
- “excessively oily”
- “sits on top of skin”
- “sticky residue”
- “transfers to pillow”
Fragrance sensitivity Rarely Noted
- “scent is too strong”
- “smells like herbs”
- “irritating fragrance”
- “prefer unscented”
Packaging concerns Rarely Noted
- “jar packaging hygiene concerns”
- “heavy glass jar”
- “prefer a pump”
- “hard to gauge amount left”
Potential breakouts Rarely Noted
- “caused blemishes”
- “cheeks broke out”
- “too rich for my pores”
- “led to small bumps”
Sources: lovi.care, sokoglam.com, iherb.com, target.com, misshaus.com, hwahae.co.kr, and more
Questions and answers
How well does Missha Time Revolution Night Repair Ampoule Cream 5X work for oily acne-prone skin?
This cream works moderately well for your oily acne-prone skin, providing balanced hydration and barrier support while lacking specific ingredients to target breakouts. To work better for this skin type, a product of this kind needs powerful ingredients that treat acne and blemishes without clogging pores.
Indian Journal of Pharmaceutical Sciences, 2016Skin Pharmacology and Physiology, 2022
Which ingredients make this cream a good fit for oily acne-prone skin?
Niacinamide helps regulate oil production while centella asiatica extract, bifida ferment lysate, and glycerin provide essential hydration and support your skin barrier. This product of this type needs acne-fighting ingredients like salicylic acid or benzoyl peroxide and lightweight, non-clogging hydrators to better target breakouts without adding extra oil.
Indian Journal of Pharmaceutical Sciences, 2016Clinical, Cosmetic and Investigational Dermatology, 2017
What does Extreme Biome do for oily acne-prone skin?
Extreme Biome helps calm oily, acne-prone skin and keeps it feeling balanced by supporting a healthy mix of helpful bacteria on the skin surface. This product is unlikely to irritate easily, but this type of skin also needs ingredients that gently clear pores and regulate oil to truly stay clear and smooth.
Journal of Cosmetic Dermatology, 2023Clinical, Cosmetic and Investigational Dermatology, 2022
What does Bifida Ferment Lysate do for oily acne-prone skin?
Bifida Ferment Lysate helps calm oily acne-prone skin by strengthening your skin barrier and lowering irritation. It is unlikely to clog pores and may help keep your skin feeling smooth and balanced.
Journal of Cosmetic Dermatology, 2023Experimental Dermatology, 2010
Where does this cream go in a skincare routine for oily acne-prone skin?
This cream fits into the routine as an evening treatment applied after cleansing and toning. It provides hydration and barrier support for your skin, but an oily acne-prone skin type needs targeted blemish-fighting ingredients and oil-balancing actives for the best results.
Can I use this cream with retinol, and in what order?
Yes, you can use this cream with retinol, and applying it after your retinol helps keep your skin calm and hydrated. A product of this type needs soothing ingredients like centella asiatica and barrier-strengthening ceramides to protect oily, acne-prone skin from dryness and irritation during retinoid use.
How often should I use this cream?
You can use this moisturizing treatment twice daily as part of your morning and evening routines to keep your skin hydrated. Regular use is unlikely to irritate your skin, though an oily and acne-prone skin type needs targeted blemish-fighting ingredients and oil-balancing actives for better results.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?
This cream is unlikely to cause purging, and the risk of breakouts is low, but reviewers note it can sometimes feel heavy or greasy on oily acne-prone skin. To better manage acne and breakouts, an oily skin type needs targeted ingredients like salicylic acid or benzoyl peroxide to clear pores.
Can I use this cream around the eyes or on my body?
You can use this moisturizing treatment safely around your eyes and on your body because its gentle formula lacks harsh ingredients that could irritate sensitive areas. Studies show that similar nourishing creams with botanical extracts and ceramides help improve skin moisture and texture in delicate periorbital regions.
Indian Journal of Pharmaceutical Sciences, 2016Skin Pharmacology and Physiology, 2022
Is this cream fragrance-free and alcohol-free?
It has no fragrance and contains drying alcohol (alcohol).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.
Skin Pharmacology and Physiology, 2022Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.
International Journal of Dermatology, 2008Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.
Experimental Dermatology, 2008
Why other moisturizers fit oily acne-prone skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Glycerin, Methyl Propanediol, Cyclohexasiloxane, Hydrogenated Polyisobutene, Caprylic Capric Triglyceride, Triethylhexanoin, Cetearyl Alcohol, Niacinamide, Dimethicone, 1,2-Hexanediol, Trehalose, Stearyl Alcohol, Beeswax, Cetyl Alcohol, Phytosteryl Isostearyl Cetyl Stearyl Behenyl Dimer Dilinoleate, Cetearyl Glucoside, Vinyl Dimethicone, Polyglyceryl-2 Stearate, Glyceryl Stearate, Palmitic Acid, Stearic Acid, Bergamot Oil Fruit, Hydroxyacetophenone, Dioscorea Japonica Root Extract, Ammonium Acryloyldimethyltaurate Vp Copolymer, Ethylhexylglycerin, Glycosyl Trehalose, Butylene Glycol, Alcohol, Bifida Lysate Ferment, Hydrogenated Hydrolysate Starch, Xanthan Gum, Adenosine, Raffinose, Glyceryl Polymethacrylate, Dextrin, Theobroma Cacao Shell Powder, Pelargonium Graveolens Oil Flower, Lecithin, Disodium Edta, Hydrogenated Lecithin, Camellia Sinensis Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Helianthus Annuus Seed Oil Sunflower Seed Oil, Jojoba Seed Oil, Camellia Japonica Seed Oil, Macadamia Ternifolia Seed Oil, Glucose, Centella Asiatica Extract, Ficus Carica Fruit Extract, Polyquaternium-51, Cetearyl Olivate, Ceramide Np, Lavandula Angustifolia Oil Lavender Oil, Citrus Aurantium Dulcis Peel Oil, Sorbitan Olivate, Phellodendron Amurense Bark Extract, Lactobacillus Ferment, Myristic Acid, Lactobacillus Acerola Cherry Ferment, Lactococcus Ferment, Leuconostoc Radish Root Ferment Filtrate, Bifida Ferment Filtrate, Lactobacillus Soybean Extract Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Monascus Extract, Sucrose Distearate, Rice Extract, Dipropylene Glycol, Biosaccharide Gum-1, Saccharomyces Ferment, Beta Vulgaris Root Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Brassica Oleracea Capitata Leaf Extract, Blueberry Fruit Extract, Solanum Melongena Fruit Extract, Anthemis Nobilis Oil Flower, Tocopherol, Sandalwood Oil, Bacillus Ferment
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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