MISSHA Super Aqua Ultra Hyalron Ampoule for acne-prone skin
10x Hyaluronic Acid
Niacinamide
Avena Sativa Kernel Extract Oat Kernel Extract
Cynara Scolymus Leaf Extract
Beta-GlucanAverage
- HighCombination Skin Fit
- AverageEffectiveness
- ExcellentSafety
Works for acne-prone skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration for your combination skin, with glycerin and multiple forms of hyaluronic acid providing humectant action, while niacinamide helps regulate oil production.
- While it provides excellent moisturizing benefits, it lacks targeted ingredients to address your specific concerns of acne, blemishes, and breakouts.
- The safety profile is good, with Tocopherol and Beta-Glucan offering soothing benefits and no harsh ingredients that would irritate your acne-prone skin.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.8Overall rating based on 300+ reviewsUsers consistently praise this ampoule for its deep, non-sticky hydration and lightweight texture that absorbs quickly, making it highly suitable for sensitive, dehydrated, and dry skin types. While the majority report a "plumping" effect and a gentle experience, a small minority mention mild tingling or frustration with the dropper packaging when the product runs low.
Highlights
Deep hydration Mostly Mentioned
- “Deeply moisturizes”
- “skin feels instantly plumper”
- “locks in moisture effectively”
- “tackles deep dryness”
Lightweight texture Mostly Mentioned
- “Not sticky at all”
- “absorbs quickly”
- “greaseless”
- “layers well under moisturizer”
Gentle formula Often Mentioned
- “Suitable for sensitive skin”
- “no breakouts”
- “gentle and non-irritating”
- “calms skin”
Generous size Sometimes Noted
- “Quantity is generous (47ml)”
- “lasts much longer”
- “good value for size”
Packaging issues Sometimes Noted
- “Dropper won't reach bottom”
- “hard to use last 1-2ml”
- “frustrating packaging design”
Mild irritation Rarely Noted
- “Slight tingling sensation”
- “potential allergens”
- “caused minor bumps”
Price concerns Rarely Noted
- “Price is a bit high”
- “wait for sales”
- “expensive without discount”
Scent concerns Rarely Noted
- “Subtle citrus scent”
- “expected unscented”
- “fragrance might bother some”
Sources: lovi.care, iherb.com, misshaus.com, yesstyle.com, hwahae.co.kr, reddit.com, and more
Questions and answers
How well does Super Aqua Ultra Hyalron Ampoule work for acne-prone skin?
This product works for your skin, though other products fit it better because it offers moderate hydration without containing targeted ingredients to address breakouts. A moisturizing treatment for acne-prone skin needs effective ingredients like niacinamide and hyaluronic acid that clear blemishes, control excess oil, and provide soothing benefits without causing irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017Scientific Reports, 2024
Which ingredients make this serum a good fit for acne-prone skin?
This moisturizing treatment works for acne-prone skin because it contains niacinamide, which helps regulate oil, along with soothing beta-glucan and tocopherol that are unlikely to irritate. However, a product of this type needs targeted blemish-fighting ingredients to be a great fit for breakouts.
Scientific Reports, 2024Journal of Cosmetic Dermatology, 2021
What does Hyaluronic Acid do for acne-prone skin?
Hyaluronic acid helps smooth out deep acne scars and delivers targeted treatments directly to pores when combined with active ingredients. It is generally well tolerated on acne-prone skin, though injected treatments should be performed by a professional.
Journal of Drugs in Dermatology, 2013Dermatologic Surgery, 2018
What does Niacinamide do for acne-prone skin?
Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Where does this serum go in a skincare routine for acne-prone skin?
This treatment goes in the evening routine after cleansing and before moisturizing. It may also be used in the morning or twice a day when your skin tolerates it well.
Can I use this serum with retinol, and in what order?
You can use this moisturizing treatment with retinol by applying it before your retinol step to help keep your skin comfortable. This type of product works best for acne-prone skin when it also includes targeted blemish-fighting ingredients and skin-soothing agents to help keep breakouts calm.
How often should I use this serum?
This treatment works best in your evening routine for simplicity and extra safety around sun exposure. It helps keep your skin soft and balanced, though acne-prone skin also needs targeted blemish-clearing ingredients to get the best results.
Can this serum clog pores, cause breakouts or purging for acne-prone skin?
This moisturizing treatment is unlikely to clog pores or cause breakouts on acne-prone skin, as it has a good safety profile with soothing ingredients and no harsh irritants. However, because it lacks targeted ingredients for blemishes, acne-prone skin needs products with blemish-fighting ingredients and oil-balancing components.
Can I use this serum around the eyes or on my body?
This moisturizing treatment is safe to use on the delicate skin around your eyes and on your body, as it has a good safety profile and is unlikely to irritate. However, because skin thickness varies across different body areas, a product for acne-prone skin needs targeted blemish-fighting ingredients and oil-balancing agents to work best on those specific concerns.
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (limonene and linalool).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.
Scientific Reports, 2024Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.
Journal of Cosmetic Dermatology, 2021Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts.
Clinical, Cosmetic and Investigational Dermatology, 2018Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model.
Skin Pharmacology and Applied Skin Physiology, 2002Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline.
Journal of Drugs in Dermatology, 2015An artichoke extract cosmetic formulation enhanced skin roughness by 19.74% and elasticity by 11.45% in human subjects compared to a placebo cream, alongside exhibiting antioxidant, anti-inflammatory, and anti-aging cellular effects.
Molecules, 2018Luteolin inhibited the mRNA expression of antimicrobial peptides and increased cornified envelope proteins in TNF-alpha/IL-17A/IFN-gamma-stimulated HaCaT cells by regulating the TRAF6/IkappaB/NF-kappaB signaling pathway.
Food Science and Biotechnology, 2025Antioxidants and luteolin topically applied decrease UV-B induced apoptosis and downregulate pro-inflammatory cytokines in kindler syndrome keratinocyte cultures.
Human Molecular Genetics, 2016Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.
Dermatology and Therapy, 2023Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.
The Journal of Dermatology, 2022Topical application of oat beta-glucan ameliorates epidermal hyperplasia and accelerates epidermal barrier recovery by promoting keratinocyte differentiation through dectin-1-mediated ERK and p38 signaling pathways that upregulate CaSR expression.
International Journal of Biological Macromolecules, 2021
Why other moisturizers fit acne-prone skin better
Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023
Ingredients
Water, Methylpropanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Niacinamide, Polyglycerin-3, Octyldodeceth-16, Ammonium Acryloyldimethyltaurate Vp Copolymer, Xanthan Gum, Ethylhexylglycerin, Pentylene Glycol, Adenosine, Methyl Diisopropyl Propionamide, Carbomer, Disodium Edta, Tromethamine, Cynara Scolymus Leaf Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Sodium Hyaluronate, Polyquaternium-51, Camellia Sinensis Leaf Water, Hydrogenated Lecithin, Beta-Glucan, Citrus Aurantium Dulcis Peel Oil, Bergamot Oil Fruit, Lavandula Angustifolia Oil Lavender Oil, Anthemis Nobilis Oil Flower, Tocopherol, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Propanediol, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Sodium Hyaluronate Crosspolymer, Magnesium Chloride, Potassium Hyaluronate, Glycine Soja Seed Extract Soybean Seed Extract, Tetrahydropiperine, Phloretin, Arginine, Limonene, Linalool
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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