make p:rem Safe Me. Relief Moisture Cleansing Foam for mature skin

How to apply

Questions and answers

What the research says

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness.

  Journal of Cosmetic Science, 2007

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

  Journal of Cosmetic Dermatology, 2020

• Topical raspberry ketone increased dermal IGF-I production through sensory neuron activation, promoting hair growth and increasing skin elasticity in mice and humans.

  Growth Hormone & IGF Research, 2008

• A liposoluble extract of Rubus idaeus cell cultures induced genes for skin hydration, stimulated ceramide production, increased extracellular matrix synthesis in cultured fibroblasts, and showed skin-hydrating capacity in vivo.

  International Journal of Cosmetic Science, 2015

• The cytotoxic effect of sodium lauryl sulphate on normal human keratinocytes was significantly decreased when combined with cocamidopropyl betaine, Tween 20, and Tween 80 at concentrations well below the critical micelle concentration.

  Skin Pharmacology and Applied Skin Physiology, 2003

Ingredients

Water, Sodium Cocoyl Isethionate, Glycerin, Sodium Methyl Cocoyl Taurate, Coco-Betaine, Potassium Cocoyl Glycinate, Potassium Benzoate, Sodium Chloride, Polyquaternium-67, Potassium Cocoate, Bergamot Oil Fruit, Citric Acid, Disodium Edta, Salvia Officinalis Oil, Sodium Acetate, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, 1,2-Hexanediol, Sodium Hyaluronate, Ethylhexylglycerin, Panthenol, Marrubium Vulgare Extract, Adansonia Digitata Fruit Extract, Hydroxyacetophenone, Rubus Arcticus Callus Extract, Dipropylene Glycol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.