Farmacy 10% Niacinamide Night Mask for mature skin
Niacinamide
Panthenol Vitamin B5
Upcycled Blueberry Seed Oil
Beta-Glucan
Shea Butter
Average
- HighNormal Skin Fit
- AverageEffectiveness
- ExcellentSafety
Works for mature skin; other nourishing masks fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Suitable for normal skin, this product offers excellent nourishing and barrier-enhancing effects due to niacinamide and beta-glucan, which improve skin resilience. Panthenol and allantoin provide hydration and soothing benefits that are supportive for your wrinkles and fine lines.
- The formulation is highly compatible with normal skin due to the antioxidant activity of niacinamide and humectant action of panthenol.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients and the presence of soothing ingredients like niacinamide and bisabolol.
How to apply
- Could be used as part of your AM or PM routine. Start using the creamy mask 3x a week and build up to daily use if your skin tolerates it.
- Apply the creamy mask after cleansing and toning , but always before your favorite moisturizer.
- Smooth an even layer of the creamy mask over your skin, avoiding any unnecessary rubbing.
- For the best results , apply the creamy mask directly onto clean and dry skin.
- Always do a patch test before your first use and avoid the delicate eye area.
People Say
★4.9Overall rating based on 1.2k+ reviewsBased on a very large amount of data, this product is highly praised for improving skin texture, refining pores, and providing deep hydration. It is generally well-tolerated by various skin types, though some users find it expensive or potentially irritating for highly reactive skin.
Highlights
Improves texture Mostly Mentioned
- “Skin feels smooth”
- “noticeably smoother”
- “refined skin texture”
Deeply hydrating Often Mentioned
- “Skin feels hydrated”
- “supple and nourished”
- “keeps skin hydrated”
Refines pores Often Mentioned
- “Smaller pores”
- “less congested”
- “refining pores”
Non-sticky texture Sometimes Noted
- “Silky smooth”
- “no sticky residue”
- “absorbs well”
High price point Sometimes Noted
- “Expensive”
- “premium price”
- “docked on value”
Causes irritation Rarely Noted
- “Mild tingling”
- “flushing in sensitive skin”
- “may irritate”
Comedogenic ingredients Rarely Noted
- “Contains shea butter”
- “not acne-safe”
- “clogged pores”
Inconvenient packaging Rarely Noted
- “Less hygienic”
- “jar is inconvenient”
- “prefer a tube”
Sources: lovi.care, farmacybeauty.com, ulta.com, dermapproved.com, sephora.sg, youtube.com, and more
Questions and answers
How well does Farmacy 10% Niacinamide Night Mask work for mature skin?
This mask works reasonably well for mature skin, helping to keep it calm and hydrated with niacinamide and panthenol. Mature skin needs a nourishing mask with powerful firming peptides and rich antioxidants to smooth fine lines and deeply support aging skin.
Journal of Cosmetic Dermatology, 2021Journal of Cosmetic Dermatology, 2025
Which ingredients make this mask a good fit for mature skin?
This mask works for mature skin thanks to niacinamide and beta-glucan, which help strengthen the skin and improve resilience. Panthenol and allantoin also provide soothing hydration that is supportive for fine lines. Mature skin generally needs formulas packed with targeted anti-wrinkle actives, deep moisturizers, and firming peptides to effectively smooth lines and restore elasticity.
Journal of Cosmetic Dermatology, 2021Journal of Cosmetic Dermatology, 2025
What does Niacinamide do for mature skin?
Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
What does Panthenol do for mature skin?
Panthenol helps mature skin by boosting hydration, smoothing dryness, and supporting the skin barrier to keep it soft and comfortable. It is unlikely to cause irritation and may help reduce the look of fine lines by improving overall moisture levels.
The Journal of Dermatological Treatment, 2017Journal of Cosmetic Dermatology, 2019
Where does this mask go in a skincare routine for mature skin?
This nourishing mask goes into your weekly evening routine, after cleansing and an enzyme powder, and before your treatment and moisturizer. Mature skin also needs targeted anti-aging ingredients like peptides, retinoids, or potent antioxidants to firm and smooth fine lines.
Journal of Cosmetic Dermatology, 2025Journal of Cosmetic Dermatology, 2021
Can I use this mask with retinol, and in what order?
You can use this mask in your evening routine along with retinol, applying it after your retinol treatment to help soothe and hydrate your skin. This type of product needs rich nourishing ingredients like ceramides, peptides, and botanical oils to better support firmness and elasticity in mature skin.
How often should I use this mask?
This mask works well as a weekly step in your routine for mature skin. A product of this type for your skin needs nourishing and barrier-enhancing ingredients like niacinamide and beta-glucan, along with panthenol and shea butter to help smooth fine lines and keep the skin soft.
Journal of Cosmetic Dermatology, 2020Journal of Drugs in Dermatology, 2015
Can this mask clog pores, cause breakouts or purging for mature skin?
This mask is unlikely to clog pores or cause breakouts for mature skin, as it contains no harsh ingredients and features soothing components that help keep skin calm. Mature skin often needs richer, deeply nourishing ingredients like shea butter and protective oils to stay soft and smooth.
Is this mask fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.
Journal of Cosmetic Dermatology, 2021A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.
Journal of Cosmetic Dermatology, 2025Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.
The Journal of Dermatological Treatment, 2017Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated.
Antioxidants, 2021Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.
Dermatology and Therapy, 2023Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.
The Journal of Dermatology, 2022Topical application of oat beta-glucan ameliorates epidermal hyperplasia and accelerates epidermal barrier recovery by promoting keratinocyte differentiation through dectin-1-mediated ERK and p38 signaling pathways that upregulate CaSR expression.
International Journal of Biological Macromolecules, 2021A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.
International Journal of Cosmetic Science, 2025
Why other nourishing masks fit mature skin better
Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline.
In Vivo, 2023Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020
Ingredients
Water, Propanediol, Niacinamide, C15-19 Alkane, Caprylic Capric Triglyceride, Glycerin, Panthenol, 1,2-Hexanediol, Cetearyl Olivate, Cetearyl Alcohol, Sorbitan Olivate, Butyrospermum Parkii Butter Shea Butter, Betaine, Blueberry Seed Oil, Tocopheryl Acetate, Beta-Glucan, Bisabolol, Allantoin, Melia Azadirachta Flower Extract, Glycogen, Coccinia Indica Fruit Extract, Lactobacillus Ferment, Corallina Officinalis Extract, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Jojoba Seed Oil, Zingiber Officinale Root Extract, Curcuma Longa Root Extract, Ocimum Basilicum Leaf Extract Flower, Ocimum Sanctum Leaf Extract, Maltodextrin, Arginine, Carbomer, Pentylene Glycol, Sodium Phytate, Melia Azadirachta Leaf Extract, Caprylyl Glycol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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