Elemis Pro-Collagen Advanced Eye Treatment for skin with dark spots

Questions and answers

What the research says

• Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability.

  Aesthetic Plastic Surgery, 2026

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation.

  Dermatologic Therapy, 2022

• Polyelectrolyte nanocomplexes of quaternized cyclodextrin grafted chitosan and low molecular weight hyaluronic acid improved skin texture and elasticity by increasing skin hydration in clinical evaluation.

  Colloids and Surfaces. B, Biointerfaces, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of a 3% horse chestnut extract gel significantly decreased wrinkle scores at the corners of the eye and lower eyelid skin compared with controls in 40 healthy female volunteers.

  Journal of Cosmetic Science, 2006

• Topical horse chestnut extract increases wound tensile strength and collagen organization in rats without inducing fibroblast to myofibroblast conversion in vitro, though it induces fibronectin-rich extracellular matrix formation.

  Molecules, 2020

• A cornflower extract containing N-feruloylserotonin reduced inflammation in vitro by neutralizing CCL17 and CCL22 and inhibiting COX-2 and 5-LOX.

  Mediators of Inflammation, 2021

• A flaxseed extract microemulgel produced statistically significant improvements compared to a placebo in skin erythema, melanin, sebum, moisture, and elasticity in 13 healthy human female volunteers.

  Pharmaceutics, 2022

• Hempseed or flaxseed oil-based lyotropic liquid crystals with the highest oil content and lecithin/Tween 80 mixture provided a 2-fold reduction in TEWL values and decreased skin erythema levels in healthy adult subjects compared to baseline.

  Acta Pharmaceutica, 2024

• Topical application of linseed, evening primrose, and olive oil emulsions accelerated wound closure in rats with excision wounds compared to untreated controls, though via different mechanisms.

  Drug Delivery and Translational Research, 2019

• Application of a cosmetic multiple emulsion containing vitamin C and wheat protein as well as a base formulation increased skin moisture in 11 human volunteers over four weeks, while producing no significant variations in skin sebum, pH, elasticity, melanin, or erythema.

  Pakistan Journal of Pharmaceutical Sciences, 2008

• The addition of polymers and hydrolysed proteins to model body wash cosmetics improves foaming properties, storage stability, and safety by reducing skin irritant potential, with the polyvinylpyrrolidone/hydrolysed wheat protein crosspolymer showing the strongest reduction effect.

  Colloids and Surfaces. B, Biointerfaces, 2015

Ingredients

Water, Propylene Glycol, Glycerin, Rice Powder Hull Powder, Ammonium Acryloyldimethyltaurate Vp Copolymer, Sclerotium Gum, Diazolidinyl Urea, Sodium Benzoate, Sodium Pca, Disodium Edta, Sodium Lactate, Potassium Sorbate, Arginine, Aspartic Acid, Hydrolyzed Wheat Protein, Pca, Centaurea Cyanus Flower Extract, Linum Usitatissimum Seed Extract, Hydrolyzed Hyaluronic Acid, Glycine, Alanine, Aesculus Hippocastanum Seed Extract, Serine, Valine, Linalool, Caramel, Threonine, Isoleucine, Proline, Parfum, Anthemis Nobilis Oil Flower Chamomile Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Lavandula Hybrida Oil, Osmanthus Fragrans Flower Extract, Phenoxyethanol, Histidine, Phenylalanine, Sodium Hydroxide, Padina Pavonica Thallus Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.