Dr. Ceuracle Tea Tree Purifine 95 Essence for mature skin

How to apply

Questions and answers

What the research says

• Topical 5% tea tree oil gel significantly improved total acne lesions and acne severity index compared to placebo in 60 patients with mild to moderate acne vulgaris, showing 3.55 times and 5.75 times greater efficacy respectively.

  Indian Journal of Dermatology, Venereology and Leprology, 2007

• Topical application of 100% tea tree oil significantly reduced histamine-induced mean weal volume compared to control in twenty-seven volunteers.

  The British Journal of Dermatology, 2002

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Hamamelis bark proanthocyanidins strongly increased the proliferation of cultured human keratinocytes and reduced transepidermal water loss and erythema formation in SLS-irritated skin, whereas the polysaccharide fraction had no effect.

  Phytochemistry, 2001

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A Hamamelis virginiana leaf extract increased LOXL1 expression twofold, decreased elafin synthesis, restored functional elastic fibers, reduced nonfunctional elastin aggregates, decreased wrinkles, and improved skin firmness.

  Journal of Cosmetic Science, 2018

• Witch hazel bark extract and hamamelitannin showed pronounced anti-inflammatory activity, supported keratinocyte migration in a wound healing assay, and inhibited Staphylococcus aureus growth, whereas their skin microbiota metabolite ellagic acid stimulated inflammatory mediator release.

  Journal of Ethnopharmacology, 2025

• Hamamelis virginiana bark extract inhibited Cutibacterium acnes-induced IL-6 release and TNF-α-induced IL-8 release in human keratinocytes without showing antibacterial or antibiofilm activities.

  Antioxidants, 2022

Why other serums fit mature skin better

• Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks.

  Journal of Cosmetic Dermatology, 2016

• Cosmetic eye and facial creams containing palmitoyl peptides, Silybum marianum seed oil, and vitamin E improve facial wrinkles, elasticity, dermal density, and skin tone in healthy volunteers with aged skin after 4 weeks of application compared to pre-application.

  Experimental and Therapeutic Medicine, 2016

Ingredients

Melaleuca Alternifolia Tree Leaf Extract, 1,2-Hexanediol, Butylene Glycol, Water, Trehalose, Ethylhexylglycerin, Citric Acid, Witch Hazel Water, Glycerin, Biosaccharide Gum-1, Sodium Levulinate, Glyceryl Caprylate, Sodium Anisate, Sodium Hyaluronate, Methyl Gluceth-20, Cellulose Gum, Portulaca Oleracea Extract, Camellia Sinensis Leaf Extract, Scutellaria Baicalensis Root Extract, Willow Bark Extract, Origanum Vulgare Leaf Extract, Lactobacillus Soybean Extract Ferment, Cinnamomum Cassia Bark Extract, Chamaecyparis Obtusa Leaf Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.