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Superoxide dismutase and hexapeptide-9

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Superoxide dismutase and hexapeptide-9: keep them apart

Keep them apart

Use them at different times of day, applying superoxide dismutase first and hexapeptide-9 later, because mixing them breaks down the active ingredients. Enzymes can break down peptides, meaning you might lose the firming and anti-aging benefits you want from your products. You can safely use both by applying them in separate morning and evening routines.

Superoxide dismutase products

Hexapeptide-9 products

Questions and answers

Can you use superoxide dismutase and hexapeptide-9 together?

No, you should keep superoxide dismutase and hexapeptide-9 apart because enzymes like superoxide dismutase can degrade peptide bonds and render hexapeptide-9 inactive. It is best to avoid combining enzymatic ingredients with peptides in the same routine.

Which goes first, superoxide dismutase or hexapeptide-9?

Keep superoxide dismutase and hexapeptide-9 apart in your routine because mixing them may degrade the peptide bonds and render the actives inactive.

Are superoxide dismutase and hexapeptide-9 good for sensitive skin?

Superoxide dismutase and hexapeptide-9 should be kept apart in your routine because combining them may degrade the peptide bonds and render the active ingredients inactive. Lovi assigns an average fit for sensitive skin when using these ingredients separately due to potential irritation risks.

Research on superoxide dismutase and hexapeptide-9

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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