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Sesderma vs Grown Alchemist

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Sesderma and Grown Alchemist are distinct skincare brands founded in Spain in 1989 and known for advanced serums, cleansers, and meticulously engineered formulas. The former is beloved for botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types best, featuring the Azelac RU Serum for acne-prone skin to refine texture and promote a radiant complexion. Meanwhile, the latter is loved for formulas that suit sensitive, dry, and combination skin best, highlighting standout options like the Hydra-Restore Cream Cleanser, Instant Smoothing Serum, and Gentle Gel Facial Cleanser for specific concerns. Both differ through their precise approaches, with the Spanish brand emphasizing specialized corrective results while the other focuses on botanical-driven daily care.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Sesderma and Grown Alchemist products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Sesderma vs Grown Alchemist products

Questions and answers

Sesderma or Grown Alchemist: which is better?

Grown Alchemist is generally better for sensitive or dry skin, where its Hydra-Restore Cream Cleanser reaches a High Lovi fit level, whereas Sesderma offers strong options like Azelac RU Serum that has a High Lovi fit for acne-prone skin and dark spots. Grown Alchemist also keeps all the products on this page fragrance-free, unlike Sesderma's serum.

What is the difference between Sesderma and Grown Alchemist?

Sesderma offers the Azelac RU Serum which has High fit for acne-prone skin and dark spots, while Grown Alchemist features the Hydra-Restore Cream Cleanser which has High fit across many skin types including dry sensitive and mature skin. Grown Alchemist products on this page list no fragrance, whereas Sesderma includes fragrance in its serum.

Which is more affordable, Sesderma or Grown Alchemist?

Neither Sesderma nor Grown Alchemist shows pricing information on this page, so affordability cannot be compared here.

Which causes fewer breakouts, Sesderma or Grown Alchemist?

Grown Alchemist fits acne-prone skin with a High level in its Hydra-Restore Cream Cleanser, whereas Sesderma achieves a High fit for acne-prone skin with its Azelac RU Serum. Azelaic acid helps reduce acne-prone breakouts.

Pharmaceutics, 2021

Which brand was founded earlier, Sesderma or Grown Alchemist?

Sesderma was founded earlier in 1989 in Spain, while Grown Alchemist was founded in 2008.

Do both Sesderma and Grown Alchemist products contain fragrance?

Grown Alchemist has no fragrance listed in any of the products on this page, whereas Sesderma includes fragrance in its Azelac RU Serum.

Which brand has products that achieve a High Lovi fit level for dry sensitive skin?

Grown Alchemist has products that achieve a High Lovi fit level for dry sensitive skin, specifically the Hydra-Restore Cream Cleanser. Sesderma products on this page only reach a Low fit for that skin type.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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