Jole vs Sesderma
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Jole and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Jole or Sesderma: which is better?
Both brands have strong picks, but Jole fits sensitive skin better with a High Lovi rating across the products on this page and zero fragrance. Sesderma's Azelac RU Serum also earns a High Lovi fit for acne-prone skin and dark spots, though it contains fragrance.
What is the difference between Jole and Sesderma?
Jole has no fragrance in the products on this page, whereas Sesderma includes fragrance in its Azelac RU Serum. For sensitive skin, Lovi fit is High with Jole and Average with Sesderma.
Which is more affordable, Jole or Sesderma?
This page does not provide pricing information for either Jole or Sesderma, so affordability cannot be compared here.
Which brand has been established longer, Jole or Sesderma?
Sesderma has been established longer, having been founded in Spain in 1989, whereas Jole was founded more recently in 2019.
Do products from Jole or Sesderma contain fragrance?
Every product on this page from Jole lists no fragrance in its ingredients, whereas the Azelac RU Serum from Sesderma contains fragrance.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.


